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纳米生物医用材料 被引量:8

Nanobiomaterials
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摘要 纳米生物材料的理论和实验研究正成为现代生物和医用材料的研究热点。随着纳米技术和材料科学、生命科学的不断交叉,纳米生物医用材料已在新型医用植入材料和介入医用材料、组织工程和再生医学材料、新型药物和基因控释载体及高效生物诊断材料领域取得较大进展。本文主要针对纳米生物医用材料在生物相容性界面、组织再生修复、基因和药物传递及生物诊断上的应用进行评述,并探讨纳米生物医用材料的发展前景。 Nanobiomaterial is a multidisciplinary scientific field with roots in life science, material science and nanotechnology. The basic and application researches of nanobiomaterials have been the hot topic in the materials research for biomedicine and biotechnology, which have developed quickly in biomedical implant and intervention medicine, tissue engineering and regenerative medicine, and drug/gene delivery system. This review focuses on the potential of nanobiomaterials including biocompatible surface, tissue engineering and regenerative materials, new drug/gene delivery system and bioanalysis system, with an attempt to explore their possible applications in clinical practice.
作者 沈家骢
出处 《中国医学科学院学报》 CAS CSCD 北大核心 2006年第4期472-474,共3页 Acta Academiae Medicinae Sinicae
关键词 纳米生物材料 生物相容性界面 组织工程和再生医学材料 基因药物传递 生物诊断材料 nanobiomaterial biocompatible surface tissue engineering and regenerative materials drug/gene delivery system bioanalysis system
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参考文献14

  • 1Andersson B.ESF scientific forward look on nanomedicine;European Science Foundation policy briefing,2004,1-6.Strasbourg,France:European Science Foundation (ESF),2004.
  • 2Hong Y,Gao CY,Shen JC,et al.Collagen-coated polylactide microspheres as chondrocyte microcarriers.Biomaterials,2005,26(32):6305-6313.
  • 3Zhang SG.Fabrication of novel biomaterials through molecular self-assembly.Nat Biotechnol,2003,21 (10):1171-1178.
  • 4Tang ZY,Kotov NA,Magonov S,et al.Nanostructured artificial nacre.Nat Mater,2003,2:413-418.
  • 5Tan QG,Ji J,Shen JC,et al,Construction thromboresistant surface on biomedical stainless steel via layer-by-layer deposition antocoagulant.Biomaterial,2003,24(25):4699-4705.
  • 6Zhu HG,Ji J,Shen JC,et al.Surface engineering of poly (DL-lactide) via electrostatic self-assembly of extracellular matrix-like molecules.Biomacromolecules,2003,4 (2):378-386.
  • 7Ren KF,Ji J,Shen JC.Construction of polycation-based nonviral DNA nanoparticles and polyanion multilayers via layer-bylayer self-assembly.Macromol Rapid Commun,2005,26(20):1633.
  • 8Ren KF,Ji J,Shen JC.Construction and enzymatic degradation of multilayered poly-l-lysine/DNA films.Biomaterials,2006,27(7):1152-1159.
  • 9Lynn DM.Layers of opportunity:nanostructured polymer assemblies for the delivery of macromolecular therapeutics.Soft Materials,2006,2:269-273.
  • 10Shen H,Tan J,Saltzman WM.Surface-mediated gene transfer from nanocomposites of controlled texture.Nat Mater,2004,3:569-574.

二级参考文献58

  • 1[1]Culver K W. Gene Therapy: A Primer for Physician. Larchmont: Mary Ann Liebert,Inc, 1996
  • 2[2]Mahato R I, Smith L C, Rolland A. Pharmaceutical perspective of nonviral gene therapy. Adv Genet, 1999, 41: 95~156
  • 3[3]Lehrman S. Virus treatment questioned after gene therapy death. Nature, 1999, 401: 517~518
  • 4[4]Mashall E. Gene therapy death promotes review of adenovirus vectors. Science, 1999, 286: 2244~2245
  • 5[5]Anderson W F. Human gene therapy. Nature, 1998, 392(Supp): 25~30
  • 6[6]Rolland A P, Mumper R J. Plasmid delivery to muscle: Recent advances in polymer delivery systems. Adv Drug Deliv Rev, 1998, 30(1~3): 151~172
  • 7[7]Lee R J, Huang L. Lipidic vector systems for gene transfer. Crit Rev Ther DrugCarrier Syst, 1997, 14(2): 173~206
  • 8[8]Luo D, Saltzman M. Synthetic DNA delivery systems. Nat Biotech, 2000,18: 33~37
  • 9[9]Nakanishi M, Akuta T, Nagoshi E, et al. Nuclear targeting of DNA. Eur J Pharm Sci, 2001, 13: 17~24
  • 10[10]Rolland A P. From genes to gene medicine: recent advances in nonviral gene delivery. Crit Rev Ther Drug Carrier Syst, 1998, 15: 143~198

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