摘要
用交叉亲和酶联免疫电泳法，对７７例ＡＦＰ阳性血清进行ＡＦＰ异质体分析。结果ＡＦｐ－Ｎ－Ｌ的比率分别为肝硬化组（８４．１４±１１０．６０）％、急性肝炎组（８１．０７±６．５９）％和慢性肝炎组（７７．５３±１１．４２）％，均显著高于原发性肝癌组（６２．８５±１７．６９）％，（Ｐ＜０．０５）。表明ＡＦＰ异质体是比ＡＦＰ更具有特异性的肝癌标志物，对原发性肝癌以及其他良性肝病的鉴别诊断有着重要的意义。
AFP heterogeneity analysis was performed in seventy-seven AFP positive sera bycross affinity enzymoimmunoelectrophoresis.ResuIt:the rates of AFp-N-L were(84.14±10.60)%in hepatocirrhosis group,(181.07±6.59)%in hepatitis group and(77.53±11.42)%in chronic hepatitis group respectively.These rates were significantly higher than that in primaryhepatoma group(62.85±17.69)%,P<0.05.Our investigation indicates that AFP heterogene-ity as a marker of primary hepatoma is more specific than AFP,and is useful in the differential di.agnosis of primary heptoma with other benign hepatic diseases.
出处
《广西医科大学学报》
CAS
1996年第2期64-66,共3页
Journal of Guangxi Medical University
