摘要
应用免疫组化ABC法对77例肺癌的石蜡切片进行KT、CEA、NSE检测。结果:肺鳞癌KT阳性率为71.7％,多为中,强阳性,仅1例腺癌呈KT弱阳性,鳞癌和腺癌的KT阳性率有极显著性差异(P<0.01);腺癌CEA阳性率为92.9％,多为中、强阳性,鳞癌CEA阳性率为45.7％,绝大多数为局灶性弱阳性,二者间的CEA阳性率有极显著性差异(P<0.01);NSE阳性仅见于小细胞肺癌。提示:KT或CEA中、强阳性有助于鉴别鳞癌和腺癌;NSE阳性有助于识别小细胞肺癌。
The determination of KT,CEA,NSE was performed on paraffin sections from 77 pulmonary carcinomas with ABC immunohistochemical staining. KT was positive expression in 71.7% of squamous cell carcinomas (SQCC). Degree of staining of KT was middle or strong in the SQCC,and weak staining for KT was present at the only one case of adenocarcinoma(ADC). There was a significant difference in the percentage of KT between SQCC and ADC(P<0. 01). CEA was positive expression in 92. 9% of ADC,in 45. 7% of SQCC,and there was a significant difference (P<0.01). CEA showed moderate or intense staining in most cases of ADC,but weak,focal staining in SQCC. The expression for NSE was observed only in small cell lung carcinomas (SCLC). It is suggested that moderate or strong staining for KT or CEA help to distinguish SQCC from ADC;and the positive expression of NSE be one of the characteristics of SCLC.
出处
《兰州医学院学报》
1996年第3期12-14,共3页
Journal of Lanzhou Medical College
关键词
肺肿瘤
免疫组织化学
诊断
鉴别
Lung neoplasms
Immunohistochemistry
Diagnosis differential
