摘要
目的观察自体骨髓干细胞移植治疗骨不连及骨缺损的疗效。方法140例患者随机分为自体髂骨移植组(A组)及自体骨髓干细胞移植组(B组)各70例,均行手术治疗,并行简单有效的内外固定。结果术后平均愈合时间A组为(7.0±2.0)个月,B组为(5.0±1.5)个月,两组间有显著性差异(P<0.05);治疗期间患者无明显不良反应。结论自体骨髓干细胞移植较传统植骨治疗骨不连及骨缺损疗程短、疗效好,无不良反应。
Objective To observe the curative effect of marrow stem cell transplant on bone nonunion and bone defection, Methods 140 patients were randomly divided into the group A （with auto-iliac bone transplant） and group B （with auto-marrow stem cell transplant）, There were 70 cases in each group, All patients in two groups were treated by operation and inside and outside fixation, Results After treatment, the average cicatrization time of group A was （7. 0 ±2. 0） months, that of group B was （5. 0 ±1. 5） months, there was a significant difference between two groups（ P 〈0.05）. There were no obvious adverse reactions found during the treatment period. Conclusion Compared with the traditional bone grafting, treating bone nonunion and bone defection by auto- marrow stern cell transplant has obvious superiority with better curative effect, short course and no adverse reactions.
出处
《中国康复理论与实践》
CSCD
2006年第8期706-707,共2页
Chinese Journal of Rehabilitation Theory and Practice
关键词
骨髓干细胞
骨髓移植
骨不连
骨缺损
： marrow stem cell
marrow transplant
bone nonunion
bone defection
