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人类疱疹病毒6型感染与风湿性关节炎关系的研究 被引量:1

Relationship between Human Herpesvirus-6 and Rheumarthritis
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摘要 目的探讨人类疱疹病毒6型(HHV-6)与风湿性关节炎之间的关系.方法采用巢式PCR方法检测38例风湿性关节炎患者外周血单个核细胞和血清中的HHV-6-DNA.结果风湿性关节炎患者HHV-6-DNA阳性率为55.26%,而对照组为52%,两组比较无显著性差异(P〉0.05).部分患者血清中存在HHV-6-DNA,提示这些患者可能存在HHV-6活动性感染.结论HHV-6感染与风湿性关节炎相关. Objective To approach the relations between human herpesvirus-6 (HHV-6) and rheumarthritis (RA). Methods Detect 38 RA cases HHV-6-DNA in the peripheral blood mononuclear cell(PBMC) and serum by using nested polymerase chain reaction. Results HHV-6-DNA positive rate of the RA patients is 55.26 %, and the control group is 52 %. Two groups have no significant difference(P 〉0.05). HHV-6-DNA exists in some of patients serum, it indicates that these patients have reactivity infection of HHV-6 probably. Conclusion HHV-6 infection correlates with RA.
出处 《北华大学学报(自然科学版)》 CAS 2006年第5期431-432,共2页 Journal of Beihua University(Natural Science)
基金 吉林大学研究生创新基金资助项目
关键词 风湿性关节炎 巢式PCR 人类疱疹病毒6型 Rheumarthritis Nested polymerase chain reaction Human herpesvirus-6
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