摘要
目的 了解四川省西昌市社区美沙酮维持治疗（MMT）对海洛因成瘾者性行为的影响情况。方法 于2004年5～7月，采用横断面调查，从社区招募海洛因成瘾者，采用问卷调查其社会人口学、近1个月性行为特征及安全套使用情况，分析美沙酮维持治疗对其近1个月性行为特征及安全套使用的影响情况。结果 在调查的346名海洛因成瘾者中，参加过MMT的占30．4％（105人），参加MMT时间的中位数为49天。单因素Y0检验和多因素Logistic回归模型统计分析结果均显示，参加MMT的海洛因成瘾者近1个月与固定性伴性行为频率增加（OR2．61，95％CI1．43～4．75），与临时性伴性行为频率降低（OR0．35，95％C10．16～0．74），提高与临时性伴的100％安全套使用率（OR21．0，95％CI3．25～135．87）。结论 该研究结果表明：我国第一批海洛因成瘾者社区美沙酮维持治疗试点项目，在减少吸毒人群艾滋病相关高危性行为方面具有一定效果。
Objective To investigate the impact of community-based methadone maintenance treatment （MMT）on sexual behavior and condom use among heroin addicts in Xichang county of Sichuan province. Methods From May to July 2004,a community-based cross-sectional survey was conducted to collect data of socio-demographics, sexual behavior and condom use in the last month among drug users.Associations of MMT with sexual behavior and condom use in the last month were analyzed. Result Of the total 346 heroin addicts investigated, 30.4 % （105/346） were receiving methadone maintenance treatment and the median treatment duration was 49 days. Both of the Chi-square and multivariate logistic regression model showed that MMT was independently associated with increased sex with regular sex partners in the last month（OR, 2.61 ; 95 % CI, 1.43 - 4.75 ）, but with decreased sex with casual sex partners in the last month （ OR, 0.35 ; 95 %C1,0.16-0.74）, and with increased consistent condom use with casual sex partners in the last month （OR, 21.0; 95 % CI,3.25 - 135.87）among heroin addicts, respectively. Conclusion The study results showed that methadone maintenance treatment was effective in reducing HIV high risk sexual behaviors among heroin addicts in the first group of pilot sites.
出处
《中国艾滋病性病》
CAS
2006年第4期307-310,共4页
Chinese Journal of Aids & STD
基金
国家自然科学基金项目(30571612
10501052)
国家十五科技攻关项目(2004BA719A01
2004BA719A02)
卫生部艾滋病防治应用性研究项目(WA2003-13)
