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脉压与心脑血管病的关系:一个大样本的随访研究 被引量:25

Relation Between Pulse Pressure and Cardio-Cerebralvascular Disease
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摘要 目的研究脉压(PP)是否与死亡有关,尤其是否与心、脑血管病有关。方法选择了1992-1993年,在韩国医疗保险公司投保年龄在40岁及以上的投保人,共有698796人,随访7年。随访开始时对每个观察对象进行健康检查并调查相关问题,随访期每2年进行1次查体。结果PP与全因死亡、心、脑血管病死亡有正相关关系。无论性别、年龄以及是否患有高血压,均得到相同结果,即随着PP升高,死亡危险性升高。但年龄越大,脉压的影响力度越弱。结论PP与全因死亡率、心脑血管病死亡率呈相关关系,在预测心脑血管病危险性时,PP可以作为一个独立的预测指标。 Objective This aim of study was to determine the relationship between pulse pressure and all cause mortality, incidence of cardiovascular disease (CVD) and cerebrovascular (CVA). Methods The cohort consisted of the beneficiaries of Korea medical insurance corporation {KMIC) aged 40 and older who underwent health examination and completed the questionnaire inquiring of health habits and past medical history in 1992 or 1993. 698 796 participants were followed up for 7 years, from 1 January, 1994 until 31 December, 2000. Resalts A linear relationship between pulse pressure(PP) and all cause mortality, incidence of cardiovascular disease and cerebrovascular disease were found in both gender and all age groups independent of BP level. Increases in PP was associated with increases in all cause mortality, incidence rate of CVD, and CVA(P〈0.01 ), however, the extent of deteriorated effect was attenuated with the increments of ages. Conclusion PP was linearly related with all cause mortality, CVD and CVA.
出处 《中华高血压杂志》 CAS CSCD 北大核心 2006年第10期830-832,共3页 Chinese Journal of Hypertension
关键词 死亡率 脉压 心血管病 脑血管病 相对危险度 Mortality Cardiovascular disease Pulse pressure Relative risk Cerebrovascular disease
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