摘要
目的:考察复方银杏注射液中银杏黄酮苷含量测定的水解条件。方法:采用正交设计法,考察水解时间(A)、水解温度(B)、盐酸浓度(C)3个因素对高效液相色谱法含量测定的影响。结果:优化后的水解条件为:水解1.5h,80℃恒温水浴,10m o l.L-1盐酸。结论:该水解条件稳定,为准确测定复方银杏注射液中银杏黄酮醇苷提供保证。
Objective： To study the hydrolytic conditions for ginkgo flavonoid glycosides in the compound ginkgo biloba injection. Methods：We used the orthogonal design.to observe the effects on the HPLC assay of the hydrolytic time, hydrolytic temperature and acidity of hydrochloric acid. Results：The optimal hydrolytic condition was that hydrolyzation needed 1.5 hours at 80℃ with 10mol/L hydrochloric acid. Conclusion： The hydrolytic conditions are steady and can offer the guarantee of determining the ginkgo flavonoid glycosides in the compound ginkgo biloba injection.
出处
《黑龙江医药科学》
2006年第5期34-35,共2页
Heilongjiang Medicine and Pharmacy
