期刊文献+

新生儿肺透明膜病72例诊治分析 被引量:12

在线阅读 下载PDF
导出
摘要 目的总结新生儿肺透明膜病(HMD)综合诊治的经验。方法对本院近3年儿科NICU综合诊治的72例新生儿HMD进行回顾性分析。所有患儿均采用氧疗,依据氧饱和度、血气检测调整给氧方式:面罩、鼻塞式CPAP、机械通气;31例应用肺泡表面活性物质(PS)固尔苏气管内给药治疗。结果治愈54例(75%),放弃治疗6例(8.33%),死亡12例(16.67%)。固尔苏治疗组较非固尔苏治疗组死亡率显著降低(χ2=4.2589 P<0.05),机械通气时间显著缩短(t=2.4252 P<0.01);胸片为Ⅲ、Ⅵ级较胸片为Ⅰ、Ⅱ级改变者机械通气时间长(t=3.376 P<0.01)。结论新生儿HMD死亡率高,应加强孕期保健;应用PS可有效改善预后;出生体质量>1500 g,胸片为Ⅰ、Ⅱ级的HMD综合诊治预后好,胸片为Ⅲ、Ⅵ级者,预后差。
作者 盖玉惠
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2006年第20期1435-1436,共2页 Journal of Applied Clinical Pediatrics
  • 相关文献

参考文献5

二级参考文献13

  • 1宋国维,甘小庄,张艳玲,宋慧琴.肺表面活性物质对重症新生儿肺炎肺氧合功能的影响[J].中华儿科杂志,1995,33(6):336-338. 被引量:28
  • 2Hoekstra RE, Jackson JC , Myers TF. et al. Improved neonatal survival following multiple doses of bovine surfactant in very premature neonates at risk for respiratory distree syndrome. Pediatrics, 1991, 88(1): 10.
  • 3Enhoming G, Shnnan A, Possmayer F, et al. Prevention of neonatal respiratory distress syndrome by tracheal instillation of surfant: a randomized clinical trial. Pediatrics, 1985, 76:145.
  • 4Soil RF, Hoekstra RE, Fangman JJ, et al. Multicenter trial of single -done modified bovine surfant extract ( Survanta ) for prevention of respiratory distress syndrome. Pediatrics, 1990, 85:1092.
  • 5Taeusch HW,Ballard RA. Avery′s disease of the newborn[ M]. 7th ed,Philadelphia:WB Saunders Company, 1998:1329 1334.
  • 6Hashimoto K,Hasegawa H,Kida Y, et al. Correlation between neuroimaging and neurological outcome in periventricular leukomalacia:diagnostic criteria [ J ]. Pediatr Int, 2001,43 (3): 240 - 245.
  • 7Jacobsson B,Hagberg G,Hagberg B, et al. Cerebral palsy in preterm infnts: a population - based case - control study of antenatal and intrapartal risk factors[ J ]. Acta Pediatr,2002,91 (8): 946 - 951.
  • 8Okihisa A, Hayakawa F, Kato T, et al. Hypocarbia in preterm infants with periventricular leukomalacia: the relation between hypocarbia and mechanical ventilation[J ]. Pediatrics,2001,107(3) :469 - 475.
  • 9Wheatley CM, Dickinson JL, Mackey DA, et al. Retinopathy of prematurity: recent advances in our understanding[J ]. Br J Ophthalmol,2002,86 (6): 696 - 700.
  • 10孙眉月.新生儿肺透明膜病[A].见:董声焕主编.现代儿科危重症医学[C].北京:人民军医出版社,1999.482.

共引文献56

同被引文献58

引证文献12

二级引证文献51

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部