摘要
目的:从炮制前后补骨脂素、异补骨脂素和微量元素含量的变化探讨补骨脂炮制的物质基础。方法:采用HPLC梯度洗脱法、电感藕合等离子体原子发射光谱法(ICP-AES)分别测定了补骨脂炮制前后的补骨脂素、异补骨脂素及六种微量元素的含量。结果:炮制使补骨脂中的微量元素Mn、Ca、Mg、Fe、Zn含量增加,但Cu含量变化不明显;补骨脂素、异补骨脂素含量增加。结论:炮制使补骨脂有效成分含量增加,提高了中药补骨脂整体生物活性。
Objective： To study the processing material foundation of Psoralea corylfolia L and compare the content of p,oralen, isopsoralen and microelement between raw Psoralea corylifolia L. and processed one. Methods ： The content of psoralen, isopsoralen and microelement were obtained by HPLC-gradient elution and ICP-AES. Results： The content of psoralen, isopsoralen and microelement Mn, Ca, Mg, Fe, Zn were raising, but the change of that of microelement Cu was not obvious. Conclusion ： The content of effective composition of Psoralea corylifolia L. is raised bv Lei-Gong method and the biological activity is improved simuhaneously.
出处
《中药材》
CAS
CSCD
北大核心
2006年第11期1142-1144,共3页
Journal of Chinese Medicinal Materials
基金
辽宁省自然科学基金资助项目(20052561)
关键词
补骨脂
炮制
补骨脂素
异补骨脂素
微量元素
Psoralea corylifolia L.
Process
Psoralen
Isopsoralen
Microelement
