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神经调节蛋白在脑缺血中的保护作用 被引量:3

The Neuroprotective Effect of Neuregulin in Cerebral Ischemia
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摘要 神经调节蛋白能调节胶质细胞的生长和分化以及小脑颗粒细胞沿胶质细胞的迁移,参与突触的形成,抑制脑缺血再灌注损伤诱导的神经元凋亡、胶质反应和炎症反应,诱导有关神经营养因子的表达,具有神经保护作用。 Neuregulin regulates the growth and differentiation of glial cells, as well as the migration of cerebellar granule cells along the glial cells. It participates in the formation of synapse, inhibits neuronal apoptosis induced by cerebral ischemia-reperfusion injury, glial reaction and inflammatory response, and induces the expression of associated neurotrophic factors, it has neuroprotective effect.
出处 《国际脑血管病杂志》 2006年第10期789-792,共4页 International Journal of Cerebrovascular Diseases
基金 山东省自然科学基金项目(No.Y2004C04)
关键词 神经调节蛋白 脑缺血 酪氨酸激酶受体 细胞凋亡 炎症反应 neuregulin cerebral ischemia ErbB receptor apoptosis inflammatory response
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