摘要
目的探讨急诊溶栓(ETT)在急性心肌梗死(AMI)再灌注治疗中的价值。方法81例患者分为急诊溶栓组和住院溶栓组。观察不同时间窗的溶栓与再通率,行补救性急诊经皮冠状动脉介入治疗(PCI)例数及死亡情况,院前及院内耽搁时间。结果急诊溶栓组院内耽搁时间比住院组少(P<0.05),发病2h内获得溶栓率显著高于住院组(P<0.05)。各时间窗溶栓再通率以2h内为最高。各时间窗血管再通率、补救性PCI数及病死率组间比较差异无显著性,死亡原因均为心源性休克或泵衰竭。结论AMI患者院前就进入AMI急诊绿色通道进行ETT,可有效缩短就诊至溶栓时间,提高再灌注成功率,更好地挽救濒死心肌。合并心源性休克或泵衰竭者病死率高,宜首选PCI治疗。
Objective To evaluate the value of emergency thrombolytic therapy（EIT） in reperfusion of acute myocardial infarction（ AMI）. Methods 81 cases were divided into ETT group and hospitalized thrombolytic therapy group. The repeffusion and recanalization rates in different time windows were observed. Primary coronary intervention （PCI） and the rates of death were also compared, as well as the time before thrombolytic therapy between the two groups. Results The time in ETT group was shorter than in hospitalization group （ P 〈 0.05 ） and the recanalization rate within 2 hours of onset was higher than in hospitalization group（ P 〈 0.05 ）. Recanalizatin rate within 2 hours was the highest in each time window. The total recanalization rate in each time window, the cases of remedial PC1 and mortality were not different between groups. All patients died of cardiogenie shock or pump failure. Conclusion AMI patients in emergent green channel who undergo ETT,which can shorten the admission time and thrombolytic therapy time and increase the success rate of recanalization, thus savipg the nearly dead heart muscle. Patients who complicated with cardiogenic shock or pump failure should be referred to PCI therapy because of their high mortality.
出处
《中国医药》
2006年第12期714-716,共3页
China Medicine
关键词
急性心肌梗死
再灌注
急诊溶栓
Acute myocardial infarction
Reperfusion
Emergency thrombolytic therapy
