摘要
目的:了解免疫因素在女性不孕中占的比率,以及流产和妇科炎症与免疫性不孕的关系。方法:用免疫金标记法检测患者血清中抗精子抗体(AsAb),抗子宫内膜抗体(EMAb)。抗绒毛膜促性腺激素抗体(hCGAb)(用ELISA法检测)。结果由于免疫因素导致的不孕占45.00%,其中以hCGAb阳性检出率最高41.34%;有流产史者AsAb、EMAb和hCGAb三种抗体阳性检出率均高于无流产史者,差异有显著性(P均<0.05);有妇科炎症者AsAb和EMAb阳性检出率均高于无炎症者,差异有显著性(P均<0.05);有流产史且伴有妇科炎症者三种抗体均高于单纯妇科炎症或者单纯流产者,且以EMAb阳性程度最显著,差异有显著性(P<0.05)。结论:流产和妇科炎症是导致女性免疫性不孕的重要原因。
Objective: To understand immunity factor ratio in female barren, miscarriage and the relation between the gynecology disease and the immunity barren. Method: The method examines sufferer's serum with the immunity gold marking method in the AsAb, EMAb, hCGAb.( use the ELISA method examination). Results: Because the barren that the immunity factor cause had 45.00%, among them checking one 41.34% with tallest rate of with the masculine gender of hCGAb; Having a miscarriage three kinds of antibody masculine genders of history AsAb, EMAb, hCGAb checks a rate all high in the one who did not have a miscarriage the history, the difference shown(P〈0.05); Having the gynecology disease AsAb to check a rate with masculine gender of EMAb all high in the one who have no disease, the difference shows (P〈0.05); Having a miscarriage the history and companions contain the gynecology disease three kinds of antibodies masculine gender rate was all high in the pure gynecology disease or simplicity the one who had a miscarriage, and showed most with the male degree of EMAb, the difference shown (P〈0.05). Conclusion: The conclusion having a miscarriage and gynecology disease might cause female immunity barren of important reason.
出处
《中国伤残医学》
2006年第4期21-22,共2页
Chinese Journal of Trauma and Disability Medicine