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ERCP术后胰腺炎的药物预防进展 被引量:12

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摘要 ERCP术后胰腺炎(post ERCP pancreatitis,PEP)定义为:ERCP术后持续24h腹痛同时伴有血淀粉酶升高3倍以上,并使患者住院时间延长2d以上。该定义为多数研究所接受,但仍有一些研究将血淀粉酶升高5倍以上或测量血脂肪酶作为划分PEP的依据。由于各研究采用的PEP的定义不尽相同。接受ERCP治疗的人群条件不同以及各研究中心技术条件的差别,近期报道的PEP发生率波动在1%~30%。但大多数非选择性的前瞻性研究认为PEP发生率约为2%~9%。多变量分析研究表明PEP发生的危险因素,详见表1。尽管近年来ERCP技术日益普及和成熟,但PEP的发生率并未明显下降,现着重将药物方面预防PEP的进展综述如下。
作者 顾超 邹晓平
出处 《中华消化内镜杂志》 2006年第6期476-478,共3页 Chinese Journal of Digestive Endoscopy
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