摘要
目的:观察腹腔镜胆囊切除术(LC)对患者肝功能和免疫功能的影响,为LC后患者的治疗与护理提供依据。方法:选择26例胆囊良性病变且肝功能正常需行胆囊切除术者为研究对象,分别在LC前1 d、术后第1、3、7天测定肝功能指标(包括ALT、AST、TBIL、ALB)和免疫功能指标(包括CD3、CD4、CD8、NK细胞的百分比、免疫球蛋白IgAI、gMI、gG及补体C3、C4含量)。结果:ALT、AST、TBIL在术后第1天较术前升高,术后第3天明显下降,术后第7天达正常水平;ALB在术后第1天较术前降低,术后第3天明显升高,术后第7天达正常水平;免疫功能指标在术后各时间点同术前相比差异无统计学意义。结论:LC后患者肝功能降低了,但可迅速恢复,免疫功能无影响。
Objective： To observe the effect of astragalus injection used before and after operation on the liver function and immune function following lapamscopic cholecystectomy （LC） in senile patients. Method： 26 patients with normal liver function before undergoing LC were used as research subjects. One day pre- operation （LC） and day 1,3, 7 post- operation, liver functions （ALT, AST, TBIL, ALB） and immune functions （CD3, CD4, CD8, percent rate of NK cell, IgA, IgM, IgG and C3, CA） were measured respectively. Results： The indices of ALT, AST, TBIL the first day post- operation were obviously higher than those of pre- operation, but decreased significantly the third day post - operation and returned to normal the seventh day post - operation. ALB decreased the first day post - operation than that of pre - operation, but ircressred significantly the third day post - operation and returned to normal the .seventh day post - operation. No statistical differences were shown in data concerning immune functions post- operation, when compared with those of pre- operation. Conclusion： Following laparoscopic cholecystectomy, liver functions of patients defensed significantly, but recovered quickly. And LC had no significant effects on immune function,
出处
《海军医学杂志》
2006年第4期311-313,共3页
Journal of Navy Medicine
关键词
腹腔镜
胆囊切除术
免疫功能
肝功能
laparoscopy
cholecystectomy
liver function
immune function
