摘要
目的了解东莞市厚街镇流动儿童免疫状况,为免疫规划提供科学依据。方法对2002-2004年厚街镇免疫规划疫苗接种情况与免疫监测相关资料进行分析。结果2002-2004年出生的流动儿童基础免疫5种疫苗(卡介苗、口服脊髓灰质炎疫苗、百白破联合疫苗、麻疹疫苗、乙肝疫苗)全程接种(覆盖)率分别是69.42%、70.17%、69.78%,均非常显著低于同年出生本地户籍常住儿童的99.36%、98.36%、97.66%(χ2分别为380.45、336.96、317.48,P值均﹤0.005)。2004年免疫监测表明,1～6岁流动儿童中乙型肝炎表面抗原抗体(抗-HBs)、麻疹IgG抗体、脊灰Ⅰ、Ⅱ、Ⅲ型中和抗体的阳性率分别是45.21%、72.37%、93.33%、97.33%、94.67%,几何平均滴度(GMT)分别是7.55mIU/ml、1∶576.10、1∶164.28、1∶288.68、1∶70.2。2004-2005年报告的麻疹病例中,流动人口占99.72%,其中0～6岁占57.45%。结论流动儿童基础免疫全程接种率、部分抗体阳性率与GMT低,存在易感人群积累,导致麻疹等传染病的流行与暴发。加强流动儿童计划免疫管理,提高免疫规划疫苗接种率,是本地区计划免疫的工作重点。
Objective To analyze the immunity status of the floating children in Houjie town of Dongguan city and provide scientific basis for setting up immunization programs for the population. Methods The data of the immunization records and surveillance on related diseases of the floating children born in 2002 to 2004 in Houjie town of Dongguan city was analyzed. Results The full coverage rates of five vaccines （BCG ,OPV,DTP,measles and Hepatitis B vaccine） of floating children born in 2002, 2003 and 2004 were 69.42%, 70.17% and 69.78%, respectively, while those of local children born in 2002, 2003 and 2004 were 99.36%, 98.36% and 97.66%, respectively. The full immunization rates of the five vaccines of floating children were significantly lower than those of local children born in 2002 to 2004 （Χ^2=380.45,336.96,317.48;P〈0.005）. The positive rates of anti-HBs IgG antibody of MV,the neutralization antibody of Ⅰ , Ⅱ and Ⅲ poliomyelitis were 45.21% ,72.37% ,93.33% ,97.33% and 94.67% , respectively, with the GMT of 7.55 mIU/ml, 1：576.10, 1：164.28, 1：288.68 and 1：70.2, respectively. The floating children accounted for 99.72% in all measles cases reported in 2004 to 2005, among which 57.45% was between 0 and 6 year-old. Conclusion The low vaccination rates of the five vaccines, low antibody positive rates and the low level of GMT of floating children lead to the accumulation of susceptible population and the outbreak or epidemic of related infectious diseases. It is suggested that it should enforce the immunization program to increase the immunization rate of the floating children.
出处
《热带医学杂志》
CAS
2007年第1期73-75,82,共4页
Journal of Tropical Medicine
关键词
流动儿童
免疫状况
分析
floating children
immunity status
analysis
