摘要
前庭诱发的肌源性电位(Vestibularevokedmyogenicpotentials,VEMP)可用于评价球囊功能及其对称性,本文总结VEMP在神经耳科学中的应用情况。首先建立VEMP的临床适用的检查方法,这些方法包括:刺激声的选择、刺激强度及给声方式,建立VEMP在振幅、阈值、潜伏期和耳间潜伏期的正常值。临床上常用于:梅尼埃病和迟发性膜迷路积水、前庭神经炎、听神经瘤、前半规管裂综合征和听神经病的诊断定位。VEMP的振幅变化较大,潜伏期的变化较大,而阈值较稳定。梅尼埃病和迟发性膜迷路积水、前庭神经炎、听神经瘤可以出现振幅的异常或引不出;梅尼埃病、迟发性膜迷路积水和听神经瘤可见振幅和潜伏期异常。听神经瘤还可见耳间潜伏期延长。听神经病主要表现为振幅的异常,振幅减低或引不出。VEMP是一种稳定的肌源性电位,双侧声刺激较为适宜。VEMP的阈值检查主要用于压力或声音敏感性眩晕;耳间潜伏期的异常主要见于桥-小脑角占位病变;振幅和潜伏期的异常一般没有特异性,可见于累及前庭下神经的病变。
Vestibular evoked myogenic potentials （VEMP） can be utilized to evaluate the saccular function. The clinical application of VEMP were summarized. The testing protocol were established and then the amplitude, threshold, latency and inter-aural latency were determined. Some conditions related to saccular function, including Meniere＇s disease/delayed endolymphatic hydrops, vestibular neuritis, acoustic neuroma, anterior semicircular canal dehiscence syndrome and auditory neurophathy. The variation of amplitude and latency of VEMP were large, where the threshold was more stable. Meniere＇s disease/delayed endolymphatic hydrops, and acoustic neuroma manifested abnormal amplitude and latency. Acoustic neuroma also had abnormal inter-aural latency. Auditory neuropathy showed abnormal amplitude or without the potentials at all. VEMP was a stable myogenic potentials and binaural simultaneous stimulation was a appropriate technique. The threshold of VEMP was used to determine pressure or sound sensitive vertigo; the abnormal interaural latency was seen mainly in the cerebellopontine angle occupying disorders; the anormal amplitude and latency had no specificity and appeared in disorders involved the pathway of inferior vestibular nerve.
出处
《中华耳科学杂志》
CSCD
2006年第4期298-302,共5页
Chinese Journal of Otology
关键词
前庭诱发肌源性电位
前庭系统
眩晕
Vestibular evoked myogenic potentials
Vestibular system
Vertigo
