摘要
自１９８７年以来，采用高选迷切加胃窦粘膜切除术（ＨＳＶ＋ＭＡ）治疗十二指肠溃疡４５例。经１～７年随访，结果无手术死亡，临床属Ｖｉｓｉｃｋ分级Ⅰ级～Ⅱ级者占９１．１％。术后胃酸分泌较术前有所降低，胃液和血清胃泌素水平术后虽然较术前显著降低，但无统计学意义。术后胃液胆酸和细菌含量较术前相比无显著变化。Ｘ线钡餐和胃镜检查未发现溃疡复发。结果表明，ＨＳＶ＋ＭＡ不仅能有效降低胃酸分泌，减少溃疡复发，而且能保存胃窦和幽门功能，防止术后肠胃返流和胃内细菌过度繁殖。
Since 1987, 45 patients with duodenal ulcer have been treated with highly selective vagotomy combined with mucosal antrectomy (HSV+MA) and followed up for 1￣7 years. The results were as follows: (1) There was no operative mortality and 91.9% of the patients belonged to Ⅰ￣Ⅱ grades; (2) The secretion of gastric acid was significantly reduced postoperatively; (3) The level of gastrin in gastric juice and serum were decreased postoperatively but it had no statistical significance; (4) No significant changes of bile acid and total bacterial counts in gastric juice were found after the operation; (5) No ulcer recurrence was observed by barium meal examination and endoscopy. Our findings suggest that HSV+MA is a better treatment for duodenal ulcer for it can not only effectively decrease acid secretion and rates of ulcer recurrence but also preserve the functions of the antrum and pylorus and prevent post operative enterogastric reflux and intragastric bacterial overgrowth.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1996年第6期531-533,共3页
Journal of Third Military Medical University
