摘要
目的:探讨晚期卵巢上皮性癌细胞减灭术后的治疗方法对其预后的影响。方法:回顾性分析1991年1月￣2002年12月我院治疗的85例晚期卵巢上皮性癌的临床资料,包括临床分期、病理类型、组织分级、术后残留癌灶大小、化疗疗程数及生存期等。结果:55例肿瘤切净者其5年生存率为50.91%,30例肿瘤基本切净的5年生存率为10.0%(P<0.05)。术后化疗≥6个疗程的5年生存率52.83%,<6个疗程的5年生存率9.38%(P<0.01)。结论:晚期卵巢上皮性癌的预后与临床分期、病理类型、组织分级、术后残留病灶大小及化疗疗程数相关,彻底的缩瘤术,重视化疗的规范化,合理选择多途径治疗,可提高疗效、延长生存期。
Objective：To investigate the relationship between therapeutics after cytoreductive surgery and prognosis in patients with advanced epithelial ovarian cancer.Methods：Retrospectively study the clinical data of 85 patients with advanced epithelial ovarian cancer who were treated from Jan 1991 to Dec 2002 in our hospital, including clincal stage, pathological style, histological grade, residual tumor size, chemotherapy courses and survival.Results：For 55 patients who had a complete, macroscopically radical cytoreduction performed, the su/vival rates at 5-year were 50.91%; for 30 pa- tients who had residual tumor, the survival rates at 5-year were 10.0%（P〈0.05）. For patients who underwent postoperative chemotherapy ≥6 courses, the survival rates at 5-year were 52.82%; for those 〈6 courses, the survival rates at 5- year were 9.38%（P〈0.01）.Conclusion：For patients with advanced epithelial ovarian cancer, prognosis is correlated with clincal stage, pathological style, histological grade, residual tumor size and chemotherapy courses. Optimal cytoreductive surgery, normative chemotherapy and rational synthetic therapy can improve curative effect, prolong survival.
出处
《中国医药导报》
CAS
2007年第01Z期32-33,共2页
China Medical Herald
关键词
卵巢上皮癌
手术
化疗
预后
Epithelial ovarian cancer,Operation
Chemotherapy
Prognosis
