摘要
目的评价颈部淋巴结磁共振（MRI）弥散加权成像（DWI）的可行性，及其在良、恶性淋巴结鉴别诊断中的价值。方法对20例鼻咽癌患者和14例志愿者进行颈部常规MRI和DWI检查，比较两种检查方法对淋巴结的显示能力，并比较正常淋巴结与转移性淋巴结之间表观弥散系数（ADC）差异的统计学意义。扫描采用基于SENSE技术的STIR-EPI-DWI。结果弥散加权成像较常规MRI能更敏感性地显示淋巴结。正常淋巴结的ADC值为（0．975±0．179）×10^-3mm^2／s，转移性淋巴结的ADC值为（0．766±0．119）×10^-3mm^2／s，两者之间的差异有统计学意义（P〈0．01），转移性淋巴结的ADC值明显低于正常淋巴结的ADC值。结论STIR—EPI—DWI能准确和更敏感地显示淋巴结，可作为淋巴结MRI成像的一种新手段，为良恶性淋巴结的鉴别诊断提供了新的方法。
Objective To evaluate the feasibility and efficacy of a new MRI imaging method-- diffusion weighted imaging （DWI） with short TI version recovery-echo planar imaging （STIR-EPI） sequence in differentiating benign cervical lymph nodes from malignant ones. Methods Twenty nasopharyngeal carcinoma patients and fourteen volunteers received both conventional MRI and DWI with STIR-EPI. Ability of detecting lymph nodes between conventional MRI and STIR-EPI-DWI was compared, and the difference of apparent diffusion coefficient （ADC） value between metastatic lymph node and normal lymph node was analyzed. Results DWI was more sensitive in detecting lymph node than conventional MRI. ADC value of metastatic lymph node （0. 766 ±0. 119） × 10^-3 mm^2/s was significantly lower than that of normal lymph node （0. 975 ± 0. 179） × 10^-3 mm^2/s （p 〈 0.01 ）. Conclusion As a new MRI imaging technique in detecting cervical lymph nodes, diffusion weighted imaging （DWI） with short TI version recovery-echo planar imaging （STIR-EPI） sequence is more reliable and sensitive than conventional MRI imaging, providing an alternative way to differentiate benign lymph nodes from malignant ones.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2007年第1期70-73,共4页
Chinese Journal of Oncology
关键词
颈淋巴结
磁共振成像
弥散加权成像
Cervical lymph nodes
Magnetic resonance imaging
Diffusion-weighted imaging
