摘要
目的探讨卡维地洛治疗慢性心力衰竭(心衰)患者对心功能的影响。方法56例慢性心衰患者随机分为卡维地洛组30例和常规治疗组26例。常规组应用血管紧张素转换酶抑制剂、利尿剂和洋地黄制剂。卡维地洛组在此其础上加用卡维地洛。结果治疗后卡维地洛组临床改善总有效率86.6%,显著高于常规治疗组65.4%,P<0.05。左室射血分数为(50.21±7.91)%,显著高于常规治疗组(41.70±5.45)%,P<0.05。结论在常规抗心衰治疗基础上加用卡维地洛,能明显改善心功能,提高左室射血分数。
OBJECTIVE To evaluate the effect of Carvedilol on cardiac function of the chronic heart failure （CHF）. METHODS 56 patients with CHF were divided randomly into two groups, carvedilol treatment group （30 cases） and generally treatment group （26 cases）, In generally treatment group, the cases were treated with ACE inhibitor , digoxin and diuretic. In carvedilol treatment group, the cases were treated with carvedilol on the basis of above generally treatment group. RESULTS In carvedilol treatment group , the total improvement rate （ 86.6% ） was significantly bighter than that in generally treatment group （ 65.4% ） （ P 〈 0.05 ）, and the LVEF （left ventficular EF） （50.21 ±7.91 ）% was significantly highter than that in generally treatment group （41.70 ± 5. 45） % （P 〈 0.05 ）. CONCLUSION In carvedilol treatment group, the cardiac function may be improved remarkably, and also in LVEF.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2007年第1期81-82,共2页
Chinese Journal of Modern Applied Pharmacy
