摘要
研究油茶肉质果、肉质叶提取液(EFF,EFY)的抗自由基、降血糖和抗癌作用。采用TBA比色法和小鼠红细胞氧化溶血抑制试验测定抗自由基作用;采用四氧嘧啶诱导糖尿病小鼠模型,分别用EFF和EFY灌胃7d测定降血糖作用;利用H22移植性实体瘤的方法研究抗癌作用。EFF具有显著消除体内自由基及抗脂质过氧化作用,与维生素E抗自由基及脂质过氧化效果相同;对实验性糖尿病小鼠血糖有明显的降低作用,接近中药消渴丸的效果;能明显抑制小鼠H22移植性实体瘤的生长,油茶肉质果组的抑瘤率为54.9%,油茶肉质叶组的抑瘤率为30.2%,对动物白细胞、脾指数、胸腺指数无明显影响。EFF和EFY能有效控制糖尿病小鼠的血糖水平,维持正常代谢,对正常血糖小鼠无影响;具有提高SOD活性,清除自由基的作用;对癌症小鼠有显著的抑癌效果,与已报道的20种具有显著抗癌作用的蔬菜相比,油茶肉质果排在第9位,油茶肉质叶排在第15位。
The anti free-radical, antihyperglycemic and anti- tumor effect of the fleshy fruit （EFF） and fleshy leaf （EFY） extract on Camellia oleifera Abel were investigated. It was found that EFF, similar with that of vitamin E, could scavenging free radical and inhibit lipid per- oxidation. In alloxan-induced diabetic mouse, EFF and EFY could decreased the serum glucose level. However, the serum glucose level of the control mouse did not changed. Both EFF and EFY exhibited high SOD activity and free radical scavenge ability. By compared with that of the twenty vegetables, all of them exhibited anti-tumor significantly, EFF and EFY rate ninth and fifteenth, respectively.
出处
《食品与生物技术学报》
CAS
CSCD
北大核心
2007年第1期46-50,共5页
Journal of Food Science and Biotechnology
基金
广东省自然科学基金(06026957)
香港霍英东基金(HK314-140436)
关键词
肉质果
肉质叶
油茶
抗自由基
降血糖
抗癌
fleshy fruit
fleshy leaf
Camellia Oleifera Abel
anti-free-radial
anti-hyperglycemic
anti-tumor
