期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

儿科临床协作研究：五年经验并展望

Clinical Cooperation Study of Pediatrics：Five-year Experience and Prospectives
原文传递
导出
摘要 纵观临床儿科与新生儿科近20-30年的发展可以发现，在80年代初以前已开始有少量单个中心的随机对照性研究结果作为判断新药、新治疗方法和新预防措施的客观依据，大部分为临床经验性报道，与当时的经济条件、技术和学术发展水平有关。80-90年代进入多中心随机对照（双盲）研究，最突出的成果是肺表面活性物质治疗新生儿呼吸衰竭临床试验的开展，在不到10年时间通过30多项多中心随机对照试验，判明了该治疗手段的先进性（有效和安全）。该治疗方法的迅速普及应用显著降低了新生儿病死率，成为儿科临床协作研究的范例。
作者 孙波 喻文亮 钱莉玲
机构地区 复旦大学附属儿科医院小儿内科小儿呼吸与危重病实验室
出处 《国际儿科学杂志》 2007年第2期79-82,共4页 International Journal of Pediatrics
关键词 研究 合作行为
分类号 R722 [医药卫生—儿科]
  • 相关文献

参考文献11

  • 1American Academy of Pediatrics. Committee on Fetus and Newborn. Use of inhaled nitric oxide[J].Pediatrics,2000, 106(2 Pt 1):344-345.
  • 2The Neonatal Inhaled Nitric Oxide Study Group. Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure[J] .N Engl J Med, 1997,336(9) :597-604.
  • 3Ballard RA, Truog WE, Cnaan A, et al. Inhaled nitric oxide in preterm infants undergoing mechanical ventilation [ J ]. N Engl J Med, 2006, 355(4) :343-353.
  • 4Kinsella JP, Cutter GR, Walsh WF, et al. Early inhaled nitric oxide therapy in premature newborns with respiratory failure[J]. N Engl J Med,2006,355(4):354-364.
  • 5American Academy of Pediatrics Committee on Fetus and Newbom. Postnatal corticosteroids to treat or prevent chronic lung disease in preterm infants[J].Pediatrics,2002,109(2) :3133-308.
  • 6Horbar JD.The Vermont Oxford Network:evidence-based quality improvement for neonatology[J].Pediatrics,1999,103(1 Suppl E):350-359.
  • 7Chinese Collaborative Study Group for Neonatal Respiratory Diseases.Treatment of severe meconium aspiration syndrome with procine surfactant:a multicenter,randomized,controlled trial[J].Acta Paediatr,2005,94(7):896-902.
  • 8新生儿呼吸疾病研究协作组.猪肺表面活性物质治疗胎粪吸入综合征的多中心随机对照研究[J].中华儿科杂志,2005,43(5):354-359. 被引量：50
  • 9Lu Y, Song Z, Zhou X, et al. A 12-month clinical survey of incidence and outcome of acute respiratory distress syndrome in Shanghai intensive careunits[J]. Intensive Care Med,2004,30(12) :2197-2203.
  • 10喻文亮,陆铸今,王莹,施丽萍,匡凤梧,张剑晖,谢敏慧,钱素云,樊寻梅,孙波.小儿急性呼吸窘迫综合征前瞻性多中心临床流行病学研究[J].中华急诊医学杂志,2005,14(6):448-453. 被引量：57

二级参考文献44

  • 1Lotze A, Mitchell BR, Bulas DI, et al. Multicenter study of surfactant (beractant) use in the treatment of term infants with severe respiratory failure. J Pediatr, 1998,132: 40-47.
  • 2Soll RF, Dargaville PA. Surfactant for meconium aspiration syndrome in full term infants (Cochrane Review). http://www.update-software. com/Abstracts/ab002054.htm.2005-04-19.
  • 3Sun B, Curstedt T, Lindgren G, et al. Biophysical and physiological properties of a modified porcine surfactant enriched with surfactant protein A. Eur Respir J, 1997,10: 1967-1974.
  • 4Herting E, Rauprich P, Stichtenoth G, et al. Resistance of difference surfactant preparations to inactivation by meconium. Pediatr Res, 2001,50: 44-49.
  • 5Tokieda K, Ikegami M, Wert SE, et al. Surfactant protein B corrects oxygen-induced pulmonary dysfunction in heterozygous surfactant protein B-deficient mice. Pediatr Res, 1999,46: 708-714.
  • 6Vazquez de Anda GF, Lachmann RA, Gommers D, et al. Treatment of ventilation-induced lung injury with exogenous surfactant. Intensive Care Med, 2001,27: 559-565.
  • 7Walti H, Polla BS, Bachelet M. Modified natural porcine surfactant inhibits superoxide anions and proinflammatory mediators released by resting and stimulated human monocytes. Pediatr Res, 1997,41: 114-119.
  • 8Cao L, Qian LL, Zhu YR, et al. Regulation of activity of nuclear factor-kB and activator protein-1 by nitric oxide, surfactant and glucocorticoids in alveolar macrophages from piglets with acute lung injury. Acta Pharmacol Sin, 2003, 24: 1316-1323.
  • 9Hilgendorff A, Rawer D, Doerner M, et al. Synthetic and natural surfactant differentially modulate inflammation after meconium aspiration. Intensive Care Med, 2003,29: 2247-2254.
  • 10Ohama Y, Ogawa Y. Treatment of meconium aspiration syndrome with surfactant lavage in an experimental rabbit model. Pediatr Pulmonol, 1999,28(1): 18-23.

共引文献104

国际儿科学杂志
2007年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部