摘要
目的:观察乳癖消和三苯氧胺联合应用治疗乳腺增生病的临床疗效,并探讨其作用机制。方法:将158例乳腺增生病患者随机分为3组:联合治疗组(n=54)、三苯氧胺组(n=52)和乳癖消组(n=52)。联合治疗组用三苯氧胺加乳癖消治疗,三苯氧胺组及乳癖消组均为单药治疗。经期停药,疗程3个月。结果:联合治疗组总有效率为94．4%,三苯氧胺组总有效率为76．9%,乳癖消组总有效率为61．5%。单药治疗组与联合治疗组间均有显著差异(P＜0．01)。结论:乳癖消与三苯氧胺合用治疗乳腺增生病疗效满意,优于单用三苯氧胺或乳癖消。
Objective：To observe the clinical efficacy of rupixiao combined with tamoxifen in the treatment of mammary gland hyperplasia （MGH）. Methods：One hvmdred fifty eight cases of MGH were randomized into 3 groups： combination of rupixiao and tamoxifen, tamoxifen alone and rupixiao alone. Results： The total effective rates of the three groups were 94.4%, 76.9%, and 61.5% respectively （P〈0.01）. Conclusion：A combination of rupixiao and tamoxifen in treating MGH is superior to either tamoxifen or rupixiao alone, which is strongly recommended in clinical practice.
出处
《中国临床医学》
北大核心
2007年第1期109-110,共2页
Chinese Journal of Clinical Medicine
关键词
乳腺增生症
乳癖消
三苯氧胺
Rupixiao
Tamoxifen
Mammary gland hyperplasia
