摘要
目的探讨血清-腹水白蛋白梯度(Serum-ascitesalbumingradient,SAAG)与门脉高压的关系,评价SAAG对预测门脉高压性食管-胃底静脉曲张破裂出血的价值。方法测定29例肝硬化腹水患者SAAG值并行胃镜检查以了解有无食管-胃底静脉曲张,以11g/L为界将29例患者分为高SAAG组及低SAAG组,采用Pearson相关分析法分析SAAG与食管-胃底静脉曲张之间的关系。29例患者中并发食管-胃底静脉曲张破裂出血者8例,非出血者21例,测定两组患者的SAAG值并进行比较。结果26例高SAAG患者中17例有食管-胃底静脉曲张,而3例低SAAG患者均无食管-胃底静脉曲张。SAAG与食管-胃底静脉曲张存在正相关关系(r=0.40,P<0.05;r=0.84,P<0.01);8例出血组患者其SAAG值为(24.24±7.18)g/L,21例非出血组患者其SAAG值为(18.27±6.06)g/L,两组比较差异有显著性(P<0.05)。结论SAAG与门脉压力密切相关且对预测门脉相关性食管-胃底静脉出血有一定临床价值。
Objective To study the relationship between serum-asicites albumin gradient （SAAG） and the portal hypertensive ascites in order to appreciate the value of SAAG on the prediction of esophageal-gastric fundus variceal bleeding. Methods 29 patients with cirrhotic ascites were examined with endoscopy. The patients were classified as high-gradient group and low-gradient group by the SAAG value of 11 g/L. The relationship between SAAG and esophagel-gastric fundus varices was studied by Pearson correlation analysis. Among the 29 patients studied, 8 patients had esophageal-gastric fundus variceal bleeding and 21 patients had no esophageal-gastric fundus variceal bleeding. Results In the 26 patients classified as high-gradient group, 17 patients had esophageal-gastric fundus variceas. In the 3 patients classified as low-gradient group, no patient had esophageal-gastric fundus variceas. The result shows the direct correlation between the level of SAAG and the degree of esophageal-gastric fundus variceas （r = 0.40, P 〈 0.05 ; r = 0.84,P 〈 0.01 ）. The mean level of SAAG in bleeding group, consisting 8 patients, was 24.24 ± 7.18g/L. The mean level of SAAG in non-bleeding group, consisting 21 patients, was 18.27 ± 6.06g/L. The result shows a significantly difference between the bleeding group and non-bleeding group（ P 〈 0.05 ）. Conclusions There is correlation between the level of SAAG and the portal venous pressure. The level of SAAG is valueable on the prediction of esoohageal-gastric fundus variceal bleeding.
出处
《临床内科杂志》
CAS
2007年第2期92-93,共2页
Journal of Clinical Internal Medicine
