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安徽省阜阳市首例H5N1型人禽流感临床报告 被引量:13

The first case of human infection by the highly pathogenic avian influenza A(HSN1 ) in Fuyang, Anhui
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摘要 目的了解人感染高致病性H5N1型禽流感流行病学和临床学特征及防治手段。方法对本院收治的1例人感染高致病性H5N1型禽流感病例的相关资料进行回顾性分析。结暴患者为26岁年轻孕妇,有病、死家禽接触史,临床表现为以急性呼吸窘迫综合征为主的全身多器官功能障碍,治疗上采取了以机械通气为主的综合性措施,治愈出院。结果提高对人感染高致病性H5N1型禽流感诊断的警惕性,及早干预是降低病死率的关键环节。 Objective To describe the epidemiologic and clinical characteristic of human infection by the highly pathogenic avian influenza A(H5N1) and to provide the evidences for making strategy on its prevention, diagnosis and treatment. Methods The data of one patient with human infection by the highly pathogenic avian influenza A(H5N1) in Fuyang Second People's Hospital in Feb. 2006 were analyzed retrospectively. Results The patient was a 26-year old pregnant woman, having a history of direct contact with sick or dead poultry. The major clinical manifestation of the case was multiple organ dysfunction syndrome (MODS) predominantly showing as acute respiratory distress syndrome (ARDS). Mechanical ventilation therapy was the most important treatment. The inpatient was cured after 33 days. Conclusions It is very important to improve awareness of human infection by highly patho- genic avian influenza A (H5N1). Early intervention is critical for reducing the mortality.
出处 《中华传染病杂志》 CAS CSCD 北大核心 2007年第1期35-37,共3页 Chinese Journal of Infectious Diseases
关键词 H5N1人禽流感 流行性感冒 急性呼吸窘迫综合征 机械通气 Human H5N1 avian influenza Influenza Acute respiratory distress syndrome Mechanical ventilation
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参考文献5

  • 1Tran TH, Nguyen TL, Nguyen TD, et al. A vian influenza A(HSN1) in 10 patients in Vietnam. N Engl J Med, 2004,350:1179-1188.
  • 2Beigel JH, Farrar J, Han AM, et al. Avian influenza A (HSN1) infection in humans. N Engl J Med, 2006, 354-884.
  • 3Yuen KY, Wong SS. Human infection by avian influenza A H5N1. Hong Kong Med J, 2005, 11:189-199.
  • 4de Jong MD, Bach VC, Phan TQ, et al. Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma. N Engl J Med, 2005, 352:686-691.
  • 5韩明锋.《传染性非典型肺炎(SARS)诊疗方案》之我见[J].中华传染病杂志,2004,22(5):355-356. 被引量:10

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