期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

内皮素系统与心力衰竭 被引量：12

Endothelin System and Heart Failure
在线阅读 下载PDF
导出
摘要 内皮素具有强烈而持久的血管收缩作用,其与慢性心力衰竭的发生、发展及疾病的预后密切相关。长期应用内皮素受体拮抗剂可改善心力衰竭患者的血流动力学、减缓左室重构、增加心脏指数、同时提高生存率。 Endothelin is a potent and long-acting vasoconstrictor. It is related closely to the occurrence,development and prognosis of chronic heart failure. Long-term treatment with endothclin-reccptor antagonist has improved haemodynamics,decreased left ventricular hypertrophy, increased cardiac output,and prolonged the survival rate of patients with chronic heart failure.
作者 倪国华 张向阳
机构地区 新疆医科大学第一附属医院心内科
出处 《心血管病学进展》 CAS 2007年第2期280-282,共3页 Advances in Cardiovascular Diseases
关键词 内皮素 心力衰竭 内皮素受体拮抗剂 endothelin chronic heart failure endothelin-receptor antagonist
分类号 R541.61 [医药卫生—心血管疾病]
  • 相关文献

参考文献25

  • 1Yanagisawa M,Kurihara H,Kimura S,et al.A novel potent vasoconstrictor peptide produced by vascular endothelial cells[J].Nature,1988,332(6163):411-415.
  • 2Rich S,McLaughlin VV.Endothelin receptor blockers in cardiovascular disease[J].Circulation,2003,108(18):2184-2190.
  • 3李天奇,李勇.内皮素与心力衰竭[J].心血管病学进展,2005,26(1):17-20. 被引量：11
  • 4Yamamoto S,Matsumoto N,Kanazawa M,et al.Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts[J].Circulation,2005,111(3):302-309.
  • 5Laflamme K,Roberge CJ,Germain L,et al.Tissue-engineered human vascular media with a functional endothelin system[J].Circulation,2005,111(4):459-464.
  • 6Sidhartha D,Mishra TK,Satpathy C,et al.Endothelins and endothelin receptor antagonists[J].JIACM,2004,5(1):55-59.
  • 7Berger R,Stanek B,Hülsmann M,et al.Effects of endothelin a receptor blockade on endothelial function in patients with chronic heart failure[J].Circulation,2001,103(7):981-986.
  • 8Leslie SJ,Spratt JCS,McKee SP,et al.Direct comparison of selective endothelin A and non-selective endothelin A/B receptor blockade in chronic heart failure[J].Heart,2005,91(8):914-919.
  • 9Givertz MM,Colucci WS,LeJemtel TH,et al.Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure[J].Circulation,2000,101(25):2922-2927.
  • 10Lüscher TF,Barton M.Endothelins and endothelin receptor antagonists[J].Circulation,2000,102(19):2434-2440.

二级参考文献31

  • 1Yanagisawa M,Kurihara H,Kimura S,et al.A novel potent vasoconstrictor peptide produced by vascular endothelial cells[J].Nature,1988,332(6163):411-415.
  • 2Howard PG,Plumpton C,Davenport AP.Anatomical localization and pharmacological activity of mature endothelins and their precursors in human vascular tissue[J].J Hypertens,1992,10(11):1379-1386.
  • 3Xu D,Emoto N,Giaid A,et al.ECE-1:a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1[J].Cell,1994,78(3):473-485.
  • 4Hosoda K,Nakao K,Hiroshi-Arai,et al.Cloning and expression of human endothelin-1 receptor cDNA[J].FEBS Lett,1991,287(1-2):23-26.
  • 5Williams DL Jr,Jones KL,Colton CD,et al.Identification of high affinity endothelin-1 receptor subtypes in human tissues[J].Biochem Biophys Res Commun,1991,180(2):475-480.
  • 6Davenport AP,O'Reilly G,Molenaar P,et al.Human endothelin receptors characterized using reverse transcriptase-polymerase chain reaction,in situ hybridization,and subtype-selective ligands BQ123 and BQ3020:evidence for expression of ETB receptors in human vascular smooth muscle[J].J Cardiovasc Pharmacol,1993,22:S22-S25.
  • 7Clozel M,Gray GA,Breu V,et al.The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo[J].Biochem Biophys Res Commun,1992,186(2):867-873.
  • 8Braunwald E.Heart disease:A textbook of cardiovascular medicine,6th ed,W.B.Saunders Co,2001,(1):526-527.
  • 9Miller WL,Redfield MM,Burnett JC Jr.Integrated cardiac,renal,and endocrineactions of endothelin[J].J Clin Invest,1989,83(1):317-320.
  • 10Monge JC.Neurohormonal markers of clinical outcome in cardiovascular disease:is endothelin the best one[J]? J Cardiovasc Pharmacol,1998,32(suppl2):S36-S42.

共引文献10

同被引文献169

引证文献12

二级引证文献214

心血管病学进展
2007年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部