摘要
目的对有关用中医药治疗内因性前葡萄膜炎文献进行系统性评价,了解研究质量的总体水平及中医药和中西医结合治疗内因性前葡萄膜炎的有效性。方法检索Medline(1966—2005年)、Em—Base(1974~2005年)、Cochrane Libmry光盘2005年第1期的Cochrane Controled Trials Register、Current Controled Trials和The National Research Register数据库;同时检索中国医学文献数据库(光盘)CBMdisc,中文生物医学期刊数据库(光盘版)CMCC,VIP中文科技期刊数据库(Web版),CNKI中国期刊全文数据库(Web版),万方数据库,中国医学学术会议论文数据库(CMAC)并辅以手工检索。结果共收集到有关中医药治疗内因性前葡萄膜炎的临床对照文献3篇,有1篇文献抽签随机,有2篇文献按就诊顺序半随机。3篇均未使用盲法。所有文献均无随机方案的隐藏。结论目前检索到国内外发表的有关内因性前葡萄膜炎中医药治疗性的文献大多以专家个人经验或专题组临床经验为主,缺少系统评价的依据。中医药治疗内因性前葡萄膜炎的疗效评价尚待根据高质量的大样本随机对照临床试验的结果进一步论证。
OBJECTIVE To assess the methodological quality of clinical studies on traditional Chinese medicine and integrated traditional Chinese and western medicine in treating endogenous anterior uveitis and to evaluate its efficacy.METHODS Medline (1966 - 2005), EMbase (1974 - 2005), Cochrane Library (2005 version of Cochrane Controlled Trials Register) were searched by computer and some Chinese journals for additional articles (such as CB- Mdisc, CMCC, VIP, CNKI, CMAC) (1980 - 2005) were searched manually.RESULTS Three randomized clinical trials/clinical controlled trials (RCTs/CCTs) were identified and assessed. The methodological quality was unsatisfactory. One article refers to the use of random lot to produce random table and 2 articles produce random table according to the visit order. And none used blind procedure. No article refers to the hide of random act. CONCLUSIONS It is obvious that the methodological quality of the study on traditional Chinese medicine and integrated traditional and western medicine in treating anterior uveitis should be improved. Further, well designed clinical trials should be performed.
出处
《中国中医眼科杂志》
2007年第2期68-71,共4页
China Journal of Chinese Ophthalmology