1Chnner KS,Jones TH.Cardiovascular effects of testosterone:implications of the "male menopause"[J].Heart,2003,89 (2):121-122
2English KM,Mandour O,Steeds RP,Diver MJ,Jones TH,Channer KS.Men with coronary artery disease have lower levels of androgens than men with normal coronary angiograms[J].Eur Heart J,2000,21 (11):890-894
3Muller M,van den Beld AW,Bots ML,Grobbee DE,Lamberts SW,van der Schouw YT.Endogenous sex hormones and progression of carotid atherosclerosis in elderly men[J].Circulation,2004,109 (17):2 074-079
4Malkin CJ,Pugh PJ,Morris PD,Kerry KE,Jones RD,Jones TH,et al.Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and quality of life[J].Heart,2004,90 (8):871-876
5Malkin CJ,Pugh PJ,Jones RD,Kapoor D,Channer KS,Jones TH.The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men[J].J Clin Endocrinol Metab,2004,89 (7):3 313-318
6Hak AE,Witteman JC,de Jong FH,Geerlings MI,Hofman A,Pols HA.Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men:the Rotterdam study[J].J Clin Endocrinol Metab,2002,87 (8):3 632-639
8Alexandersen P,Haarbo J,Christiansen C.The relationship of natural androgens to coronary heart disease in males[J].Atherosclerosis,1996,125 (1):1-13
9Kuller LH.Hormone replacement therapy and risk of cardiovascular disease:implications of the results of the Women's Health Initiative[J].Atherioscler Thromb Vase Biol,2003,23 (1):11-16
10Kamigaki AS,Siscovick DS,Schwartz SM,Psaty BM,Edwards KL,Raghunathan TE,et al.Low density lipoprotein particle size and risk of early-onset myocardial infarction in women[J].Am J Epidemiol,2001,153 (10):939-945
3[1]Hautanen A,Manttari M,Marnninen V, et al.Adrenal androgens and testosterone as coronary risk factors in the helsindi heart stidy. Athersclerosis,1994,105:191-200.
4[2]Sewdarsen M, Vythilingum S, Jialal I, et al.Abnormalities in sex hormones are a risk factor for premature manifestation of coronary artery disease in South African Indian men. Atherosclerosis, 1990,83:111-117.
5[3]Huber L A, Scheffler E, Poll T, et al. 17 beta-estradiol inhibits oxidation and cholesteryl estar formation in cultured macrophages. Free Radical Commun, 1990,8:167-175.
6[4]Mitchell L E, Sprecher D L, Borecki I B, et al. Evidence for an association between dehydroepiandrosterone sulfate and nonfatal premature myocardial infarction in males. Circulation, 1994,89: 89-93.
7[5]Peter A, Horie H, Deluea C, et al. The ralationship of natural androgens to coronary heart disease in males. Atherosclerosis, 1996,125: 1-13.
8Ling S,Dai A,Williams MR,et al. Testosterone (T) enhances apoptosis-related damage in human vascular endothelial cells [J].Endocrinology,2002,143(3):1119-25.
9Hanke H,Lenz C,Hess B,et al. Effect of testosterone on plaque development and androgen receptor expression in the arterial vessel wall[J]. Circulation,2001,103(10):1382-5.
10Alexandersen P,Haarbo J,Byrjalsen I,et al. Natural androgens inhibit male atherosclerosis:a study in castrated,cholesterol-fed rabbits[J]. Circ Res,1999,84(7):813-9.
2American Diabetes Association. Diagnosis and classification of diabetes mellitus [ J ] . Diabetes Care, 2004, 27 Suppl 1 : S5-S10.
3Kapoor D, Malkin CJ, Channer KS, et al. Androgens, insulin resistance and vascular disease in men [ J ] . Clin Endocrinol ( Oxf ), 2005, 63 ( 3 ) : 239-250.
4Muller M, van den Beld AW, Bots ML, et al. Endogenous sex hormones and progression of carotid atherosclerosis in elderly men [ J ]. Circulation, 2004, 109 ( 17 ) : 2074-2079.
5Haddad RM, Kennedy CC, Caples SM, et al. Testosterone and cardiovascular risk in men : a systematic review and meta-analysis of randomized placebo-controlled trials [ J ] . Mayo Clin Proc, 2007, 82 ( 1 ) : 29-39.
6Rhoden EL, Ribeiro EP, Teloken C, et al. Diabetes mellitus is associated with subnormal serum levels of free testosterone in men [ J ] . BJU Int, 2005, 96 ( 6 ) : 867-870.
7Pitteloud N, Hardin M, Dwyer AA, et al. Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men [ J ] . J Clin Endocrinol Metab, 2005, 90 ( 5 ) : 2636-2641.
8Raz I, Eldor R, Cernea S, et al. Diabetes : insuhn resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage [ J ] . Diabetes Metab Res Rev, 2005,21 (1): 3-14.
