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痉挛型脑性瘫痪MRI研究 被引量:4

Study of Magnetic Resonance Imaging in Spastic Cerebral Palsy
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摘要 目的探讨颅脑MRI与脑瘫类型、患儿胎龄之间的关系。方法回顾性分析224例痉挛型脑瘫患儿的MRI检查和临床资料。结果224例患儿痉挛型偏瘫27例、双瘫149例、四肢瘫48例;MRI异常201例(89.7%),其中偏瘫、双瘫、四肢瘫的异常率分别为100%、87.2%和91.7%。痉挛型双瘫以脑室周围白质软化(PVL)最常见,发生率79.2%,其他类型脑损伤少见。痉挛型四肢瘫脑损伤多种多样,以PVL、足月儿类型脑损伤、先天发育畸形为主要表现,发生率分别为45.8%、20.8%和18.8%。足月儿痉挛型偏瘫以半侧损伤为主,临床表现为一侧肢体运动障碍,上肢重,下肢轻;未成熟儿痉挛型偏瘫表现为单侧或双侧PVL,临床表现为下肢重、上肢轻的偏瘫。152例PVL患儿中,发生于未成熟儿108例(71.1%)、足月儿44例(28.9%)。足月儿类型脑损伤22例,发生于足月儿20例(90.9%)。未成熟儿脑损伤类型主要为PVL,主要见于未成熟儿脑瘫,也可发生于足月儿脑瘫。足月儿类型脑损伤主要见于足月儿脑瘫,未成熟儿少见。结论颅脑MRI表现与脑瘫的类型、出生胎龄密切相关。 Objective To investigate the relationship between magnetic resonance imaging(MRI) and the type of cerebral palsy (CP) and gestational age at birth. Methods The MRI and clinical data of 224 CP children with spastic type were analyzed retrospectively. Results Among these children, 27 cases had spastic hemiplegia, 149 had spastic diplegia, and 48 had spastic tetraplegia. 201 cases (89.7%) had abnormal MRI result. The abnormal rate of MRI in spastic hemiplegia, diplegia and tetraplegia were 100%, 87.20% and 91.7 %, respectively. Periventricular leukomalacia (PVL) was observed mostly in children with spastic diplegia, other types of brain lesions were uncommon. In spastic tetraplegia the lesions were more varied. Three predominated types of MRI abnormalities were: PVL (45.8 % ), term-type brain injuries (20.8 % ) and congenital brain abnormalies (18.8 % ). Unilateral lesions were observed mostly in children with hemiplegia spastic diplegia born at term who showed unilateral motor disorder and upper extremity were heavier than lower extremity. Unilateral and bilateral PVL were observed in children with hemiplegia spastic diplegia born at preterm who showed lower extremity were heavier than upper extremity. Of 152 cases with PVL, 108 cases (71.1 %) were preterm infants and 44 cases (28. 9%) were term infants. Of 22 cases with term-type brain injuries, 20 cases (90.9%) were term infants. PVL was most observed in preterm brain injuries and was observed most in preterm children but was also in term children. Termtype brain injuries (border-zone infarct, basal ganglia-thalamic lesion, subcortical leukomalacia, and multicystic encephalomalacia) were observed most in term and rare in preterm children. Conclusion The MRI findings in CP show a good correlation with type of CP and gestational age.
出处 《中国康复理论与实践》 CSCD 2007年第4期386-388,共3页 Chinese Journal of Rehabilitation Theory and Practice
关键词 脑性瘫痪 磁共振 出生胎龄 cerebral palsy magnetic resonance imaging gestational age
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参考文献19

  • 1中华医学会儿科学分会神经学组.小儿脑性瘫痪的定义、诊断条件及分型[J].中华儿科杂志,2005,43(4):262-262. 被引量:1104
  • 2Barkovich AJ. Pediatric Neuroimaging[M]. 3rd ed. Lippincott : Williams & Wilkins, 2000 : 157-282.
  • 3Hashimoto K, Hasegawa H, Kida Y, et al. Correlation between neuroimaging and neurological outcome in periventricular leukomalacia: diagnostic criteria[J]. Pediatr Int,2001,43:240-245.
  • 4Mulas F, Smeyers P, Tellez de Meneses M, et al. Periventricular leukomalacia~ neurological and radiological sequelae and long term neuropsychological repercussions[J]. Rev Neurol, 2000,31:243-252.
  • 5龙晚生,罗学毛,梁长虹,李晓群,苏荣森,梁健强,陈曼琼.儿童脑室周围白质软化症的临床和MRI诊断[J].中华放射学杂志,1998,32(5):303-305. 被引量:19
  • 6Himmelmann K, Hagberg G, Beckung E. The changing panorama of cerebral palsy in Sweden. Ⅸ. Prevalence and origin in the birth-year period 1995-1998[J]. Acta Paediatr, 2005,94 : 287-294.
  • 7侯梅,赵荣安,于荣,赵建慧,李玉堂.早产和足月儿脑性瘫痪临床与影像学特点探讨[J].中华物理医学与康复杂志,2004,26(1):38-41. 被引量:9
  • 8侯梅,范希文,李玉堂,于荣,郭洪磊.脑性瘫痪儿童的MRI特征[J].中华儿科杂志,2004,42(2):125-128. 被引量:27
  • 9Jaw TS, Jong YJ, Sheu RS, et al. Etiology, timing of insult, and neuropathology of cerebral palsy evaluated with magnetic resonance imaging [J].J Formos Med Assoc, 1998,97:239-246.
  • 10Kwong KL, Wong YC, Fong CM, et al. Magnetic resonance imaging in 122 children with spastic cerebral palsy [J].Pediatr Neurol, 2004,31 : 172-176.

二级参考文献40

  • 1中华医学会儿科学分会神经学组.小儿脑性瘫痪的定义、诊断条件及分型[J].中华儿科杂志,2005,43(4):262-262. 被引量:1104
  • 2Volpe JJ.Neurology of the newborn.Philadelphia:Saunders,2001,217-297.
  • 3Kiortsis D,Xydis V,Drougia AG,et al.The height of the pituitary in preterm infants during the first 2 years of life:an MRI study.Neuroradiol,2004,46:224-226.
  • 4Volpe JJ.Neurobiology of periventricular leukomalacia in the premature infant.Pediatr Res,2001,50:553-562.
  • 5Resch B,Vollaard E,Maurer U,et al.Risk factors and determinants of neurodevelopmental outcome in cystic periventricular leukomalacia.Eur J Pediatr,2000,159:663-670.
  • 6Follett PL,Deng W,Dai W,et al.Glutamate receptor mediated oligodendrocyte toxicity in periventricular leukomalacia:a protect-ive role for topiramate.J Neurosci,2004,24:4412-4420.
  • 7Borch K,Greisen G.Blood flow distribution in the normal humanpreterm brain.Pediatr Res,1998,43:28-33.
  • 8Tsuji M,Saul JP,Plessis A,et al.Cerebral intravascular oxygenation correlates with mean arterial pressure in critically ill premature infants.Pediatrics,2000,106:625-632.
  • 9Pichler G,Urlesberger B,Schmolzer G,et al.Effect of tilting on cerebral haemodynamics in preterm infants with periventricular leucencephalomalacia.Acta Paediatr,2004,93:70-75.
  • 10Pichler G,Boetzelar MC,Muller W,et al.Effect of tilting on cerebral hemodynamics in preterm infants.Biol Neonate,2001,80:179-185.

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