摘要
目的探讨调肝脾方对佐剂性关节炎大鼠红细胞免疫功能的影响。方法采用健脾和肝、除痹止痛为原则组方,以补肝肾方、火把花根为阳性对照组,建立AA大鼠模型,随机分为调肝脾方组、补肝肾方组、芬必得组、火把花根片组、正常对照组、模型组6组,观察各组对AA大鼠足肿胀度及红细胞免疫功能的影响。结果调肝脾方能明显降低AA大鼠原发与继发性关节肿胀度,表现出较好的抗炎作用,并能显著增强红细胞的免疫功能。结论调肝脾方具有明显的抗炎作用,其作用机理与增强红细胞免疫功能有关。
Objective To study the influence of the means of attempering the liver and the spleen on red blood cell immune function in adjucant arthritis （AA） rats. Methods The arthritis model was induced by intracutaneously injection of complete Freud＇s adjutant in the right hind foot pad of rat. Th rats are randomly divided into 6 groups ： the means of attempering the liver and the spleen group, the means of complementing the liver and the kidney group, Fenbid group, Huobahuagen pian group, normal control group, and model group and the foot swelling degree and the red blood cell immunity function of AA rats. Results The means of attempering the liver and the spleen could obviously reduce the foot swelling degree, and of AA rats observed showed fairy anti - inflammntory effect. The red blood cell immune function could notably be strengthened. Conclusion The means of attempering the liver and the spleen has obvious anti - inflammation function, and the mechanism of action is relevant to strengthen the red blood cell immune function.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2007年第4期869-870,共2页
Lishizhen Medicine and Materia Medica Research
关键词
调肝脾方药
佐剂性关节炎
RBC-C3b受体花环率
RBC-IC花环率
The means of attempering the liver and the spleen
Adjuvant arthritis
RBC-C3 b reception body garlend rate
RBC-IC garland rate
