摘要
目的分析城市中小学生肠易激综合征（IBS）的患病率、分布特征、致病的相关危险因素及焦虑性情绪障碍状况。方法采用多级整群随机抽样方法，对福建省两个地级市中4826名中小学生进行流行病学问卷调查。结果①校正后符合Manning及罗马Ⅱ诊断标准IBS的期间患病率分别是52．16％及17．10％，以高中生居多，男女患病率差异无统计学意义（P〉0．05）。②Logistic回归分析揭示，年级、喜食辛辣或生冷食物、胃肠道感染、经常服用抗生素、遗传、经常因IBS症状而就诊、进食时吞咽困难、经常采用吞气来帮助终止打嗝、纳差、心情压抑11种因素为最具可能性的危险因素，其OR值均〉1。③4826名学生中有焦虑性情绪障碍倾向者占22．53％，男性17．84％，女性26．45％，两者差异有统计学意义（P〈0．01）。④在儿童焦虑性情绪障碍筛查表（scARED量表）5个领域的分值比较中，IBS学生高于非IBS学生，IBS就诊学生高于未就诊学生。结论①IBS是城市中小学生的常见病及多发病，患病率随年龄增长而上升；②不良饮食习惯、胃肠道感染、滥用抗生素、遗传及精神心理因素等可能是诱发城市中小学生IBS致病的相关危险因素；③焦虑性情绪障碍倾向发生率随年龄增长而上升。
Objective To study the prevalence, the distribution characteristics, the related risk factors and the association with anxiety state of irritable bowel syndrome（IBS） among the adolescents in Chinese cities. Methods Four thousands eight hundred and twenty six elementry, middle and high school students in Fujian province were recruited by a stratified, randomized cluster sampling to fill a questionnaire. Results ① The adjusted prevalence of IBS was 52.16% according to the Manning criterion and 17. 10% according to the Rome Ⅱ criterion. There was no significant difference between male and female（ P 〉 0. 05）, but high school students had the highest prevalence of IBS. ② Eleven risk factors were identified by logistic regression analysis（OR 〉 1 and P 〈 0.05） ,including age（odds ratio 1.86）, excessive intake of pepper（odds ratio 1.18） and cold foods （odds ratio 1.15）, the history of gastrointestinal tract infection（odds ratio 1.33） and antibiotics abuse（odds ratio 1.57）, genetic predisposition（odds ratio 1.67）, health seeking behavior（odds ratio 1.63）, dysphagia （odds ratio 1.38）, the air swallowing behavior for hiccup termination（odds ratio 1.21）, decreased food appetite（odds ratio 1.49） and depression （odds ratio 1.43）. （3） The prevalence of anxiety among 4826 students was 22. 53%. The anxiety prevalence was lower in male（17. 84%） than femal（26. 45%） students （ P 〈 0.01 ）. ④ The students with IBS reported higher scores on all SCARED subscales than those without IBS. The IBS students with the health seeking behavior also reported higher scores on all SCARED subscales than those IBS students without the health seeking behavior. Conlusions ① IBS is a common disorder among the adolescents and the prevalence of IBS increases with age. ② Bad diet habit, gastrointestinal tract infection, abuse of antibiotics, genetic predispostion and psychological factors are relative risk factors associated with IBS among the students in cities. ③ The prevalence of anxiety increases with age.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2007年第3期169-173,共5页
Chinese Journal of Digestion
关键词
肠易激综合征
青少年
流行病学
Irritable bowel syndrome
Adolescent
Epidemiology
