摘要
目的研究肝脏切割手术仿真系统的方法。方法取肝门部保留完好的完整肝脏,分别以不同颜色灌注材料对肝动脉、门静脉、下腔静脉、肝静脉和胆管系统进行灌注、固定、铸型、包埋、冰冻和铣切,获取连续肝脏断面图像数据集。数据集图像经配准和分割后,使用 MIMICS 9.0软件进行肝脏三维重建,采用自由设计模型系统及其附带软件(GHOST)和力反馈设备(PHANTOM)建立虚拟肝脏切割手术环境系统,并对肝脏左外叶切除术和右肝切除术进行了模拟。结果肝脏管道灌注和铸型良好,铣切后获取连续肝脏断面图像910张,图像清晰,三维重建肝脏模型形态逼真,在建立的虚拟肝脏切割手术环境系统中,沉浸感强,交互性好。PHANTOM 可对肝脏模型进行随意放大、缩小、旋转等控制,通过 PHANTOM 操纵"虚拟手术刀"对肝脏模型进行随意切割。结论在力反馈设备的基础上进行虚拟肝脏切割手术、仿真手术的过程和结果基本符合临床实际情况。
Objective To investigate the methodology of mimic resection system on liver. Methods Hepatic arteries, portal vein, inferior cava vein, hepatic veins and biliary ducts of liver with integrate hepatic portal were perfused with filling materials in different colors. And then the sample was embedded, frozen and slice-cut to obtain serial sectional images. After image registration and segmentation, the 3D reconstruction model which contained the liver＇s surface and its internal structures was constructed with MIMICS 9.0. Based on the freeform modeling system and its accessories （ the software GHOST and the force-feedback equipment PHANTOM） ,the virtual hepatectomy system was established which could manipulate the virtual scalpel to perform optional resection on virtual liver model. Results After slice-cutting the cast liver,910 serial cross-section images were obtained sharply and clearly. The 3D reconstructed liver model looked like the liver sample exactly, and could be magnified, contracted and rotated. In the virtual surgery system with good interaction, powerful immersion and great imagination, the virtual scalpel could be manipulated to perform optional resection on 3D liver model with the haptic device （PHANTOM）. Conclusions The 3 D visualized liver and the virtual hepatectomy system has been satisfactorily developed using the hepatic serial sectional images. The process of simulative operation was consistent with clinical practice.
出处
《中华外科杂志》
CAS
CSCD
北大核心
2007年第11期753-755,共3页
Chinese Journal of Surgery
基金
国家自然科学基金(30470493)
广东省科技计划资助项目(2003C34303)
广东省自然科学基金研究团队资助项目(粤科基办字[2006]5号)
国家高技术研究发展(863)计划资助项目(2006AA02Z346)
关键词
肝脏
图像配准
图像分割
三维重建
虚拟手术
Liver
Image registration
Image segmentation
Three dimensional reconstruction
Virtual surgery
