摘要
目的:了解骨科围手术期预防性应用抗菌药,评价应用的合理性。方法:查阅2005年1～12月骨科病历810份,对其中符合围手术期要求的592份病历预防性应用抗菌药物的品种、联合用药、用药时间、切口愈合进行统计分析。结果:骨科围手术期患者抗菌药物总的使用率为97.13%(575例),主要药物种类为β-内酰胺酶抑制剂复方制荆(44.69%)、头孢菌素类(27.83%)、喹诺酮类(23.48%);其中单用、二联和三联用药分别为:93.04%(535例)、6.61%(38例)和0.35%(2例);平均疗程4.89d;手术切口甲级愈合率96.11%(569例)。结论:加强抗菌药物的使用管理,规范围手术期抗菌药物的使用原则,对术后抗感染至关重要。
Objective ： To find out the situation of the use of antimicrobials in perioperative patients of orthopedics and to evaluate the rationality of use. Method： During January-december of 2005, 810 cases of orthopedics were checked, as to it＇s win 592 preventions of case of meet the perioperative period requests kinds of the administrated antimicrobials, combined administration, course and operation incisions healed etc. Statistics and analytical were performed. Result： The hospital＇s orthopedics antimicrobials total utilization rate that the patients during perioperative was 97.13% （575 example）, the main kinds of drugs is compound preparations of beta- Lactamase inhibitors （44.69%）, cephalosporins （ 27.83 % ）, quinolones （ 23.48 % ）. Among them single administration, two and three combined administration were：93.04% （535 example） ,6.61% （38 example） and 0.35% （2 example） respectively. Average therapeutic course was 4.89 days ; The rate of the operation incisions healed by first intention as 96.11% （ 569 example）. Conclusion： Strengthen the usage management of antimicrobials, to standardized usage principle of antimicrobials during perioperative period, to the anti-infects is very important after operation.
出处
《中国药师》
CAS
2007年第6期577-579,共3页
China Pharmacist
关键词
围手术期
抗菌药物
骨科
Perioperative period
Antimicrobial
Orthopedics
