摘要
目的 本研究旨在探讨癔球症与慢性胃窦炎的相关性以及诊治方法和疗效观察.方法 将我院1999-2006年12月的内科门诊及住院有癔球症同时伴有慢性上腹部不适、嗳气等症状的患者纳入本组研究.本组共86例,男20例,女66例,年龄36～71岁,平均（49±6）岁.观察治疗前及治疗4周后的临床症状、上消化道内镜、幽门螺杆菌检查.随机分为三组,分别给予抗胃炎、抗焦虑、抗胃炎加抗焦虑联合治疗. 结果癔球症者一般同时伴胃炎症状,内镜下均显示不同程度的胃窦炎表现,同时幽门螺杆菌（HP）显示阳性.给予抗焦虑同时抗胃炎治疗4周后,患者临床症状基本缓解或明显好转,胃镜显示胃窦炎治愈或明显好转,多数HP转阴性.而单用抗焦虑或抗胃炎药物无明显疗效. 结论癔球症常因情绪变化而诱发,其可能是慢性胃窦胃炎加重的重要临床症状,同时也是功能性胃肠疾病的一种类型,癔球症可能为胃十二指肠运动障碍所致,联合用药可获满意疗效.
Objective To study the correlation between globus sensation and chronic antral gastritis, Methods Eighty-six out-and in-patients with globus sensation and chronic gastritis from 1999 to 2006 were enrolled in the study. The symptoms were observed, gastroscopy was conducted, and helicobacter pylori （Hp） were tested before and after the treatment lasting four week, The patients were divided into three groups at random so that the therapeutic outcomes could be judged. Results Globus sensation was usually complicated with chronic gastritis and positive Hp. After four weeks＇ combined treatment, the clinical symptoms, including those of globus sensation and gastritis, disappeared or were improved in the combined treatment group, and Hp turned negative in most of the patients. On the contrary, the patients in the other two groups with simple treatment had no clear improvements. Conclusion Globus sensation relative to emotional change may be not only an important sign suggesting chronic gastritis but also a type of functional gastrointestinal disorders （FGIDs）. We believe that gastroduodenal motility disorder may lead to globus sensation. Combined treatment for globus sensation acts as the best.
出处
《临床军医杂志》
CAS
2007年第3期374-375,共2页
Clinical Journal of Medical Officers
关键词
癔球症
慢性胃窦炎
胃镜
多虑平
globus sensation
chronic antral gastritis
gastroscopy
doxepin
