脑红蛋白与缺氧缺血性脑损伤
被引量:1
Neuroglobin and hypoxic-ischemic brain injury
摘要
继血红蛋白和肌红蛋白之后,德国人Burmester等在2000年首次发现了另一类存在于人和小鼠脑内的携氧球蛋白:脑红蛋白(neuroglobin,Ngb)。作为球蛋白家族中的一员,Ngb在脑缺血缺氧状态下对神经元保护起着重要的作用。
出处
《中华神经医学杂志》
CAS
CSCD
2007年第6期563-565,共3页
Chinese Journal of Neuromedicine
关键词
脑红蛋白
缺血缺氧
神经保护
Neuroglobin, Hypoxia-ischemia
Neuroprotection
参考文献21
-
1Burmester T, Weich B, Reinhardt S, et al. A vertebrate globin expressed in the brain[J]. Nature, 2000, 407(6803): 520-523.
-
2Wystub S, Laufs T, Schmidt M. Localization of neuroglobin protein in the mousc brain[J]. Neurosci Lett, 2003, 346(1-2): 114-116.
-
3王航雁,邓美玉,王静,王萍,安涛.脑红蛋白基因在大脑和不同组织细胞中的表达[J].军医进修学院学报,2004,25(4):318-320. 被引量:10
-
4Pesce A, Dewilde S, Nardini M. The human brain hexacoordinated neuroglobin three-dimensional structure[J]. Micron, 2004, 35(1-2): 63-65.
-
5Pesce A, Dewilde S, Nardini M. Human Brain Neuroglobin Structure Reveals a Distinct Mode of Controlling Oxygen Affinity [J]. Structure, 2003, 11(9): 1087-1095.
-
6Fuchs C, Heib V, Kiger L, et al. Zebrafish reveals different and conserved features of vertebrate neuroglobin gene structure, expression pattern, and ligand binding[J]. J Biol Chem, 2004, 279 (23): 24116-24122.
-
7Sun Y, Jin K, Mao XO, et al. Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury[J]. Proc Natl Acad Sci USA, 2001,98(26): 15306-15311.
-
8Sun Y, Jin K, Peel A, et al. Neuroglobin protects the brain from experimental stroke in vivo[J]. Proc Natl Acad Sci USA, 2003, 100 (6): 3497-3500.
-
9Rayner BS, Duong TT, Myers S J, et al. Protective effect of a synthetic anti-oxidant on neuronal cell apoptosis resulting from experimental hypoxia re-oxygenation injury [J]. J Neurochem, 2006, 97(1): 211-221.
-
10Uzan J, Dewilde S, Burmester T, et al. Neuroglobin and Other Hexacoordinated Hemoglobins Show a Weak Temperature Dependence of Oxygen Binding [J]. Biophys J, 2004, 87 (2): 1196-1204.
二级参考文献6
-
1Burnmenster T, Weich B, Reinhardt S,et al. A vertebrate globin expressed in the brain[J]. Nature, 2000, 407:520-523.
-
2Chenggang Zhang, Chunli Wang, Meiyu Deng, et al.Full-length cDNA cloning of human neuroglobin and tissue expression of rat neuroglobin[J]. Biochem Biophys Res Commun, 2002, 290(5): 1411- 1419.
-
3Yunjuan Sun. Neuroglobin is up-regulated by and protects neurous from hypoxic-ischemic injury[J]. PNAS, 2001, 98(26): 15306-15311.
-
4Crawford MJ. Goldberg DE. Role for the salmonella flavohemoglobin in protection from nitric oxide[J]. J Biol Chem,1998,273:12543-12547.
-
5FI Gel U, Merx MW, G Decke A, et al. Myoglbin: A scavenger of bioactive NO[J]. Proc Natl Acad Sci, 2001,98(2):735-740.
-
6王春丽,张成岗.人脑红蛋白(NGB)全长cDNA序列的克隆[J].生物化学与生物物理进展,2002,29(6):946-951. 被引量:7
共引文献36
-
1李同方,刘霞,孙雪婧,杜晓华.脑红蛋白在成年牦牛脑中的表达研究[J].西北农林科技大学学报(自然科学版),2015,43(6):1-6. 被引量:3
-
2陈秀莲,陈瑞.脑红蛋白与缺血性脑损伤[J].首都医科大学学报,2005,26(1):93-95. 被引量:1
-
3赵守才,储照虎,吴家幂.脑红蛋白与脑缺血[J].国外医学(脑血管疾病分册),2005,13(5):364-366. 被引量:4
-
4李谋,刘小林,张成岗.胞红蛋白酵母双杂交载体的构建与表达[J].生物技术通讯,2005,16(6):615-617. 被引量:1
-
5潘冬生,魏学忠,冯新莉,冯思哲.脑出血模型大鼠脑组织脑红蛋白的表达[J].中国临床康复,2006,10(6):97-99. 被引量:5
-
6李谋,王春丽,刘小林,张成岗.钠钾泵β2亚基C末端编码区酵母双杂交载体的构建与表达[J].西北农林科技大学学报(自然科学版),2006,34(7):1-4.
-
7高贵山,于晓军,徐小虎.脑红蛋白与脑损伤研究现状[J].实用医学杂志,2007,23(5):765-767. 被引量:3
-
8刘振芳,张晓,张镛.脑红蛋白及其在神经疾病中的作用[J].临床神经病学杂志,2007,20(2):151-153.
-
9潘冬生,章翔,冯新莉,魏学忠.脑出血大鼠脑红蛋白表达与脑含水量变化[J].中华神经外科疾病研究杂志,2007,6(4):349-351. 被引量:7
-
10储照虎,赵守才.脑梗死后脑红蛋白的表达及其保护机制[J].中华老年医学杂志,2007,26(10):783-787. 被引量:4
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-
1Trimarchi S,Nienaber C A,Rampoldi V,et al.Role and results of surgery in acute type B aortic dissection:insights from the International Registry of Acute Aortic Dissection (IRAD)[J].Circulation,2006,114(1 suppl):1357-1364.
-
2Gaul C,Dietrich W,Friedrich I,et al.Neurological symptoms in type A aortic dissections[J].Stroke,2007,38 (2):292-297.
-
3Roach G W,Kanchuger M,Mora-Mangano C,et al.Adverse cerebral outcomes after coronary bypass surgery[J].N Engl J Med,1996,335(25):1857-1863.
-
4Nancy A,Nussmeier M D.A review of risk factors for adverse neurologic outcome after cardiac surgery[J].J ECT,2002,34 (1):4-10.
-
5Davila-Roman V G,Murphy S F,Nickerson N J,et al.Atherosclerosis of the ascending aorta is an independent predictor of long term neurologic events and mortality[J].J Am Coll Cardiol,1999,35(5):1308-1316.
-
6Buth J,Harris P L,Hobo R,et al.Neurologic complications associated w ith endovascular repair o f thoracic aortic pathology; incidence and risk factors.a study from the European Collaborators on Stent /Graft Techniques for Aortic Aneurysm Repair (EUROSTAR) registry[J].J Vasc Surg,2007,46(6):1103-1110.
-
7Sullivan T M,Sundt T M 3rd.Complications o f thoracic aortic endugrafts:spinalcord ischemia and stroke[J].J Vasc Surg,2006,43(supplA):85A-88A.
-
8张怡村,徐善水.NF-KB在脑缺血缺氧再灌注损伤中的双重作用[J].中华神经医学杂志,2008,7(6):638-641. 被引量:10
-
9邹小明,刘鑫,李梅,王武军.主动脉弓部疾病的外科治疗[J].实用医学杂志,2009,25(11):1835-1837. 被引量:4
-
10赵初环,林洁,冯霞飞,谢强丽,曹艳君,刘庆华,孙成超.急性Stanford A型主动脉夹层围术期并发症分析[J].实用医学杂志,2010,26(19):3660-3661. 被引量:9
-
1刘娟,姚国恩,蒋晓江.脑红蛋白[J].国外医学(脑血管疾病分册),2004,12(6):470-472.
-
2尹静,张祥建,李俐涛,杨燚.大鼠脑缺血后脑组织脑红蛋白mRNA的动态表达及保护机制研究[J].第三军医大学学报,2008,30(23):2247-2248.
-
3邓美玉,张成岗,王春丽,王航雁,周婉琼.大鼠缺氧缺血性脑损伤脑组织中脑红蛋白基因表达的变化[J].中华病理学杂志,2002,31(3):261-262. 被引量:24
-
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-
5尹静,场燚,李俐涛,张祥建.脑红蛋白与缺血缺氧性脑损伤[J].国际脑血管病杂志,2008,16(5):380-383. 被引量:2
-
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-
7夏斌,李莉,邵福源,赵忠新.细胞间粘附分子-1在多发性硬化患者中变化的临床意义[J].中华神经科杂志,1999,32(3):188-188. 被引量:3
-
8王航雁.携氧球蛋白的研究进展[J].军医进修学院学报,2003,24(3):239-240. 被引量:2
-
9青木.德国人住院,亲友不用陪[J].养生保健指南,2015,0(1):99-99.
-
10尚爱加,周定标,高艳,邓亚仙,张成岗.沙鼠前脑缺血后脑红蛋白的表达变化[J].中华医学杂志,2004,84(16):1390-1392. 被引量:2