摘要
目的评价经直肠超声检查及f-PSA/t-PSA比值在PSA正常的前列腺占位性病变中应用价值。方法综合分析131例PSA正常前列腺占位患者的经直肠前列腺超声表现及其中35例f-PSA/t-PSA比值,并与穿刺病理结果相对照。结果①131例患者中,结节位于内腺者25例[良性前列腺增生(BPH)17例,前列腺癌(PCa)5例,慢性肉芽肿性炎3例],位于外腺者103例(BPH82例,PCa19例,平滑肌瘤1例,炎性假瘤1例),弥漫性病变3例(均为PCa);②35例测量f-PSA的患者中,f-PSA/t-PSA比值在BPH和PCa组分别为0.27±0.12、0.21±0.11;③癌结节相对增生结节来说,体积较大、边界欠清、形态不规则、结节内血流检出率较高。结论①PSA正常的前列腺占位中,大部分为良性病变;②f-PSA/t-PSA比值对PSA正常的BPH及PCa鉴别没有应用价值;③经直肠前列腺超声检查对PSA正常前列腺占位性病变的良恶性有较好的鉴别作用,能对穿刺活检患者进行进一步的筛选。
Objective To evaluate the clinical value of transrectal ultrasound （TRUS） examination of the prostate and f-PSA/t-PSA in the diagnosis of prostatic space occupying lesions in which the PSA were normal. Methods One hundred and thirty-one cases whose PSA were normal were observed and comparative analysis of the f-PSA/t-PSA and their characterizations of TRUS were compared with pathological results. Results ①Among the 131 cases, there were 25 lesions located in inner-gland （BPH 17, PCa 5, Chronic Granulomatous Inflammation 3）, and 103 in outer-gland （BPH 82, PCa 19, Inflammatory Pseudotumor 1, Leiomyoma 1）, and 3 diffused lesions （all PCa） ; ②Among the 35 patients who had been tested the figure of f-PSA, the f-PSA/t-PSA in hyperplastic group was 0. 275±0. 12, and 0. 215±0.11 in cancer group;③The lesions in the cancer group revealed more bigger, and the rims more unclear, and the shapes more irregular, and the ratio of observed flow signals were more higher than those in the hyperplastic group. Conclusion ①Most of the lesions found in prostates were benign when their PSA were normal; ②The f-PSA/t-PSA had no clinical value in the differentiation between BPH and PCa when their PSA were normal;③TRUS examination of the prostate have important value in distinguishing hyperplastic lesions and cancer lesions in the prostatic space occupying lesions whose PSA were normal, and can help to screen biopsy cases.
出处
《中国医学影像技术》
CSCD
北大核心
2007年第5期752-754,共3页
Chinese Journal of Medical Imaging Technology
