摘要
目的探讨复方丹参注射液对梗阻性黄疸患者术后肝功能的影响。方法将梗阻性黄疸患者随机分为对照组(n=126)及术后12h使用复方丹参注射液的治疗组(n=126),分别测定其手术前后外周血ALT、AST、Tbil及肿瘤坏死因子(TNF)水平变化。结果术后第24h,治疗组AST、ALT、TNF水平均显著低于对照组,差异有统计学意义(P<0.05),术后第72hALT,ASTTB和TNF水平显著低于对照组,差异有统计学意义(P<0.05)。结论术后早期使用复方丹参注射液有利于梗阻性黄疸患者术后肝功能恢复。
[Objective] To investigate the effect of post-operative treatment with alvia miltiorrhiza on the liver function of patients with obstructive jaundice. [Methods] 256 patients with obstructive jaundice were randomly divided into 2 groups （n =126 each）. All patients were carried out surgery to remove the obstruction. The therapeutic group received Radix Salvlae Miltiorrhizae extract 50 mL i.v.d on 12h after surgery. The levels of AST, ALT, TBIL and TNF in peripheral blood were determined on the 24 h and 72h after surgery. [Results] On the 24 h after surgery, a significant difference was shown in the levels of AST, ALT, TNF of the therapeutic group and that of control group （P 〈0.05）; on the 72 h after surgery, a significant difference was shown in the levels of Tbil of the therapeutic group and that of control group （P 〈0.05）. [Conclusions] Post-operative treatment with Alvia miltiorrhiza plays an active role in recovery of liver function of the patients with obstructive jaundice and reduces the chance of liver failure after operation.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2007年第12期1478-1480,共3页
China Journal of Modern Medicine
关键词
丹参
梗阻性黄疸
肝功能
alvia miltiorrhiza
obstructive jaundice
liver function
