摘要
目的探讨辛伐他汀治疗高脂血症的临床疗效。方法口服辛伐他汀治疗高脂血症96例,每次20mg,晚间顿服,1次/d,连续服用8周。结果辛伐他汀可明显降低血清胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)(P<0.01),对高密度脂蛋白胆固醇(HDL-C)水平有升高作用(P<0.01),未出现严重不良反应。结论辛伐他汀治疗高脂血症,疗效明显。
Objective To investigate the effect of simvastatin on patients with hyperlipidenfia. Methods Ninety-six patients with hyperlipidemia received simvastatin 20 mg in the evening every day for 8 weeks. Results After 8-week treatment, the serum eoncentrations of total cholesterol, triglyceride and LDL cholesterol were decreased remarkably（ P 〈 0.01 ）, Meanwhile, the serum HDL-eholesterol concentration was increased （P 〈0.01 ）. No serious side effect was observed. Conclusions Imvastatin is effective for patients with hyperlipidemia.
出处
《实用全科医学》
2007年第7期595-596,共2页
Applied Journal Of General Practice
关键词
辛伐他汀
高脂血症
临床疗效
Simvastatin
Hyperlipidemia
Clinical efficacy
