摘要
以二乙酸碘苯(PIDA,2)为催化剂,分别由3,4-二甲氧基--α(3,4-二甲氧苯基)-肉桂酸(5a)和(Z-2-(3,4-二甲氧苯基)-3-(3,4-二甲氧苯基)-丙烯腈(5b)为原料,合成了相应的2,3,6,7-四甲氧基-9-羧基菲(6a)和2,3,6,7-四甲氧基-9-氰基菲(6b),经1H NMR测试技术表征为关环产物,产率分别为65.83%和64.76%。
Two key intermediates toward tylophorine, 2,3,6,7-tetramethoxyphenanthrene-9-carboxylic acid （6a） and 2,3,6,7-tetramethoxy-9-cyanophenanthrene （ 6b）, were prepared from （E） -2,3-bis （ 3,4-dime- thoxyphenyl） acrylic acid （5a） and （Z） -2,3-bis （ 3,4-dimethoxyphenyl ） acrylonitrile （ 5b）, under the catalysis of phenyliodine diacetate（PIDA,2）. Their yields were 65.83% and 64. 76% respectively. Their structures were characterized by means of ^1H NMR.
出处
《应用化学》
CAS
CSCD
北大核心
2006年第12期1419-1421,共3页
Chinese Journal of Applied Chemistry
关键词
二乙酸碘苯
催化剂
关环
phenyliodine diacetate, catalyst, annulation
