摘要
目的：探讨运用动态心电图心率变异性（HRV）方法对阻塞性睡眠呼吸暂停综合征（OSAHS）进行初步检测，评价其临床意义。方法：选择研究对象98例，全部经过整夜多导睡眠仪（PSG）监测，根据睡眠呼吸暂停低通气指数（AHI）≥5次／小时为标准进行分组，OSAHS患者58例，对照组40例。两组同时行24小时动态心电图监测，获取HRV数据进行统计学分析。结果：OSAHS组患者与对照组对比：（1）白天HRV无显著性差异；（2）夜间HRV明显降低，两组有显著性差异（P〈0．05）。结论：（1）OSAHS患者夜间HRV明显降低，交感-迷走神经功能失衡，迷走神经功能受损：（2）可以运用动态心电图HRV对OSAHS患者进行初步检测。
Objective To investigate the application of heart rate variability （HRV） in obstructive sleep apnea-hypopnea syndrome（OSAHS）, and evaluate its clinic meaning. Methods All 98 subjects were monitored overnight by polysomnography（PSG）. When AHI ≥5/h was taken as the cut-point, There were 58 patients in the OSAHS group and 40 in the control group according to the result of PSG. At the same time, two group subjects both were recorded Holter and HRV were analyzed . Results Campared with the control group： （1） the values of HRV in day weren＇t significantly changed in the OSAHS group. （2） the values of HRV in night （including time domian and frequency domain） were significantly lower in the OSAHS group . There were obvious differences （P〈0.05） between the two groups. Conclusions （1） HRV reduce obviously in OSAHS patients in night. The results indicate that pneumogastric nerve function is disordered in OSAHS patients. （2） The application of HRV to detect initial OSAHS is available and effective .
出处
《国际医药卫生导报》
2007年第14期11-14,共4页
International Medicine and Health Guidance News
基金
江门市科技局科研立项课题（2005-34号）
