摘要
目的:观察丁咯地尔、灯盏细辛注射液联合应用治疗急性脑梗死的疗效与安全性。方法:93例急性脑梗死患者随机分为治疗组(52例)和对照组(41例)。治疗组给予丁咯地尔200mg+生理盐水500mL静脉滴注,灯盏细辛注射液30mL+生理盐水250mL静脉滴注,每日各1次;对照组给予注射用血塞通400mg+生理盐水250mL静脉滴注,每日1次。疗程均为14d。结果:治疗组与对照组总有效率分别为94.2%和78.0%,2组比较有显著性差异(P<0.05)。结论:灯盏细辛注射液与丁咯地尔联合应用治疗急性脑梗死,疗效确切、安全、不良反应少。
OBJECTIVE: To observe efficacy and safety of Buflomedil hydrochloride injection plus Fleabane injection in treating acute cerebral infarction.METHODS: A total of 93 patients with acute cerebral infarction were randomly divided into two groups: the treatment group( n = 52) was assigned to receive Buflomedil hydrochloride(200mg) + 500mL normal saline plus Fleabane injection(30mL) + 250mL normal saline by iv gtt qd for 14d; while the control group (n = 41) to receive Xuesaitong for injeciton (400mg) + 250mL normal saline by iv gtt qd for 14d. RESULTS: The total effective rates for treatment group vs. control group were 94.2 % vs. 78.0%, showing significant difference between the two groups(P 〈 0.05) . CONCLUSION : The combination of Buflomedil hydrochloride injection and Fleabane injection is effective and safe for acute cerebral infarction, and it had less ADRs.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第21期1655-1657,共3页
China Pharmacy
关键词
灯盏细辛注射液
丁咯地尔
急性脑梗死
疗效观察
Fleabane injection
Buflomedil injection
Acute cerebral infarction
Observation of curative effects