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血管紧张素Ⅱ2型受体与心肌重构关系的研究 被引量:1

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摘要 血管紧张素Ⅱ(AngⅡ)在维持正常心脏稳态和心肌重构中都发挥重要作用。过去的研究显示,AngⅡAT1介导AngⅡ在成年心肌的大部分生物学效应,而AT2拮抗AT1。近年的研究发现,在心肌重构以及应用ARBs和ACEI治疗心血管疾病过程中,心肌AT2的效应可能取决于组织中AT2/AT1的比值,并受AT2过度激活持续时间长短的影响。
出处 《国际心血管病杂志》 2007年第4期277-280,共4页 International Journal of Cardiovascular Disease
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