摘要
用氯喹灌胃大鼠可致生精障碍，电镜下发现服氯喹组最早有Sertoli细胞溶酶体变化。形态计量发现细胞溶酶体数目略减少（P＞0．05），体积增大（P＜0．01）。作者还讨论了Sertoli细胞溶酶体的变化对精子发生的意义。
Spermatogenic arrest can be induced by chloroquine gavage in rat. In Sertoli cell, the earliar obvious effect was about the lysosomes. The number of lysosomes in Sertoli cell decreased (P>0.05) but the volume increased (P<0.01). This is a quantitative analysis about the lysosomes in Sertoli cell under pathological condition. The importance of lysosomes in Sertoli cell of spermatogenesis was emphasized.
出处
《上海第二医科大学学报》
CSCD
1997年第1期16-18,共3页
Acta Universitatis Medicinalis Secondae Shanghai
基金
国家自然科学基金!39230200
