摘要
采用微波辐射加热新技术，对环缩会反应进行了初步研究，合成了乙亚胺、喹唑酮-4、双酮酞嗪和二羟基哒嗪等杂环药物或药物合成中间体．与传统方法相比，产率接近．但其反应速度极大地加快，反应时间从几小时缩短为几分钟，相差几十倍～几百倍．
Ring-closing condensation reaction was studied and ethyliminum . 4 (3H)-quinazolinone, phthalic hydrazide and maleic hydrazide were synthesized by microwave irriation in a few minutes- Compared with conventional method, the method of microwave irriation accelerated reactions apparently.
出处
《华西药学杂志》
CAS
CSCD
北大核心
1997年第1期21-22,共2页
West China Journal of Pharmaceutical Sciences
基金
华西医科大学药学院科研基金
关键词
微波辐射
环缩合反应
药物合成
Microwave irriation Ring-closing condensation reaction
