摘要
目的分析ICU颅脑损伤患者肺部感染的发生率、感染类型、菌群变化等因素,探讨防范措施。方法对ICU内117例颅脑损伤患者进行医院感染调查。结果31例发生肺部感染,感染率为26.5%;由患者痰标本经细菌学检验分离出致病菌112株,阳性例数较多的为革兰阴性菌,其敏感的抗菌药物为亚胺培南/西司他丁、头孢哌酮/舒巴坦、阿米卡星;对耐亚胺培南/西司他丁革兰阳性球菌对万古霉素、复方新诺明敏感;真菌感染呈增多趋势,对氟康唑耐药增多至50.0%。结论医院感染有多重耐药、多重感染的特点,故应合理使用抗菌药物,建立严格的保护性隔离措施。
OBJECTIVE To analyze the incidence of pulmonary infection, the type of infection, the factors of bacterial colony change and so on among brain damage patients and to discuss the eountermeasures. METHODS Totally 117 brain damage patients in ICU were investigated about hospital infection. RESULTS From them 31 eases were with pulmonary infection, the infection rate was 26. 5%. From their sputa were isolated bacteriologically 112 strains of pathogens, the Gram-negative bacilli were dominant. The sensitive antibiotics were imipenem/eilastatin, eefoperazone/sulbaetum and amikaein. The resistant to imipenem/eilastatin Gram-positive eoeei were sensitive to vaneomyein and sulfamethoxazole/trimethoprim. The fungal infection tended to grow, its resistance rate to flueonazole was increased upto 50.0%. CONCLUSIONS In the hospital infection multi-antibiotic resistance, and multiple infection are its characteristic, it should reasonably use the antibiotic, and establish the strict protection and isolation measures.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第7期809-810,共2页
Chinese Journal of Nosocomiology
关键词
肺部感染
颅脑损伤
ICU
Pulmonary infeetion
Brain damage
Inteqsive care unit
