摘要
近年来,随着宏基因组学、蛋白质组学和代谢组学等技术的发展,工业微生物技术在资源、医药和手性合成等领域已经成为热点技术,并开拓了电子和纳米技术等新的应用领域。本文综述了几项最新的工业微生物技术,主要包括:微生物环氧化水解酶催化合成手性二醇、微生物甲酸脱氢酶用于再生氧化还原反应的辅因子、通过噬菌体展示技术得到纳米级金属丝、代谢网络改造和重建用于传统发酵生产以及有机溶剂耐受菌和宏基因组技术的应用。
Recently, with the development of the metagenomics, proteomics, metabolomics etc., the industrial microbial technology is under the way of innovation, and is exploiting the new field, such as the electronic technology and nano-micro technology. This paper describes several latest industrial microbial technologies in detail, which are the synthesis of the chiral diols by epoxide hydrolase from microbie, cofactors regeneration for redox with FDH, production of nano/micro wire by the phage display, metabolic network rebuilding for conventional fermentation and the application of the organic solvent tolerance and the metagenomics technology.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2007年第7期1223-1228,共6页
Progress in Chemistry
关键词
工业微生物
微生物技术
代谢组学
宏基因组
有机溶剂耐受
industrial microbiology
microbial technology
metabolomics
metagenomics
solvent tolerance
