期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

脊髓损伤后星形胶质细胞的病理变化及相关治疗措施的进展 被引量：3

在线阅读 下载PDF
导出
摘要 脊髓损伤（spinal cord injury，SCI）往往预后较差．致残率高。其病理过程尚不十分清楚，治疗也一直是困扰医学界的难题。脊髓损伤后星形胶质细胞（astmcyte，AS）的病理变化及其相关的治疗措施一直是研究的重点。笔者就近年来这一领域的研究进展综述如下。
作者 李建明 初同伟
机构地区 第三军医大学新桥医院骨科
出处 《中国脊柱脊髓杂志》 CAS CSCD 2007年第8期632-634,共3页 Chinese Journal of Spine and Spinal Cord
关键词 星形胶质细胞 脊髓损伤 病理变化 治疗 INJURY 致残率高 病理过程 进展综述
分类号 R285.5 [医药卫生—中药学]
  • 相关文献

参考文献20

  • 1朱舟,王伟,谢敏杰,余勇飞,陈晨,杜鹏.CDK抑制剂olomoucine对星形胶质细胞增殖活化的影响[J].华中科技大学学报（医学版）,2005,34(2):159-163. 被引量：9
  • 2Bernaudin M,Tang Y,Reilly M,et al.Brain genomic response following hypoxia and re-oxygenation in the neonatal rat identification of genes that might contribute to hypoxia-induced ischemic tolerance[J].J Biol Chem,2002,277 (42):39728-39738.
  • 3Morita M,Kozuka N,Itofusa R,et al.Autocrime activation of EGF receptor promotes osciuation of glutamate-induced calcium increase in astrocytes cultured in rat cerebral cortex[J].J Neurochem,2005,95 (3):871-879.
  • 4Albrecht PJ,Dahi JP,Stoltfus OK,et al.Ciliary neurophic factor activates spinal cord astrocytes,stimulating their production and release of fibroblast growth factor-2,to increase motor neutron survival[J].J Exp Neurology,2002,173(1):46-62.
  • 5Struve J,Maher PC,Li YQ,et al.Disruption of the hyaluronanbased extracellular matrix in spinal cord promotes astrocyte proliferation[J].Glia,2005,52 (1):16-24.
  • 6Holley JE,Gveric D,Whatmore JL,et al.Tenascin C induces a quiescent phenotype in cultured adult human astrocytes[J].Glia,2005,52(1):58-58.
  • 7Gimenez Y,Ribotta M,Menet V,et al.The role of astrocytes in axonal regeneration in the mammalian CNS[J].Prog Brain Res,2001,132:587-610.
  • 8West H,Richardson WD,Fruttiger M.Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes[J].Development,2005,132 (8):1855 -1862.
  • 9Hobohm C,Gunther A,Grosche J,et al.Decomposition and long-lasting downregulation of extracellular matrix in perineuronal nets induced by focal cerebral ischemia in rats[J].J Neurosci Res,2005,80(4):539-548.
  • 10Kozuka N,Itofusa R,Kudo Y,et al.Lipopolysaccharide and proinflammatory cytokines require different astrocyte states to induce nitric oxide production[J].J Neurosci Res,2005,82(5):717-728.

二级参考文献15

  • 1蔡文琴，实用免疫细胞化学与核酸分子杂交技术，1994年，82页
  • 2Yu A C H，J Neurosci Res，1991年，30卷，1期，72页
  • 3Stenevi U,Bjerre B,Bjorklund A et al.Effects of localized intracerebral injections of nerve growth factor on the regenerative growth of lesioned central noradrenergic neurons. Brain Res, 1974, 69:217
  • 4Norton W T, Aquino D A, Hozumi I et al. Quantitative aspects of reactive gliosis: a review. Neurochem Res, 1992, 17:877
  • 5Manthrope M, Adler R, Varon S et al. Development, reactivity and GFAP immunofluorescence of astroglia-containing monolayer cultures from rat cerebrum. J Neurocyto,1979, 8:605
  • 6Kornyei Z,Gzirok A,Vicsek T et al.Proliferative and migratory responses of astrocytes to in vitro injury. J Neurosci Res, 2000, 61:421
  • 7Mandell J M,Gocan N C,Vandenberg S R.Mechanical trauma induces rapid astroglial activation of ERK/MAP kinase: evidence for a paracrine signal. Glia, 2001, 34:283
  • 8YU A C, Lee Y L, Eng L F. Astrogliosis in culture: the model and the effect of antisense oligonucleotides on glial fibrillary acidid protein synthesis. J Neurosci Res, 1993, 34:303
  • 9Zhang Z G,Bower L,Zhang R L et al.Three-dimensional measurement of cerebral micro-vascular plasma perfusion, glial fibrillary acidic protein and microtubule associated protein-2 immunoreactivity after embolic stroke in rats: a double fluorescent labeled laser-scanning confocal microscope study. Brain Res, 1999, 844: 55
  • 10Lefrancois T,Fages C,Peschanski M et al.Neuritic outgrowth associated with astroglial phenotypic changes induced by antisense glial fibrillary acidic protein (GFAP) mRNA in injured neuron astrocyte cocultures. J Neurosci, 1997, 17:4121

共引文献11

同被引文献71

引证文献3

二级引证文献16

中国脊柱脊髓杂志
2007年 第8期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部