摘要
为了控制癌痛，观察硫酸吗啡控释片治疗癌痛的疗效，作者于１９９５年２月至１９９６年５月用硫酸吗啡控释片治疗中、重度癌痛４８例。结果：镇痛的显著有效率（完全＋中度缓解）和有效率分别为７９．２％（３８／４８）和９１．７％（４４／４８）；疼痛的程度减轻，治疗后疼痛级数（３．６±１．４）小于治疗前（７．８±１．２，Ｐ＜０．０５）；生活质量有明显改善，治疗后Ｋａｒｎｏｆｓｋｙ评分（６７±９）高于治疗前（３９±１１，Ｐ＜０．０５），副作用主要为便秘。结果提示：硫酸吗啡控释片在第三阶梯镇痛药中作为首选药，具有较好的临床应用价值。
For controlling cancer pain and evaluating analgesic effect of morphine sulphate release tablets, 48 cases of moderate and sever cancer pain were treated with morphine sulphate controlled release tablets from February 1995 to May 1996. Results: The remarkable response rates (complete and moderate remission) and the relief rates were 79.2%(38/48) and 91.7%(44/48) respectively. The pain was alleviated after treatment, pain grade 3.6±1.4( P <0.05) was smaller than before (pain grade 7.8±1.2)( P <0.05). Additionally ,the patients had a significant superior activity for living quality. The karnofsky mark after treatment (67±9) was higher than before (39±11)( P <0.05).The main side effect was constipation.The results demonstrated that this drug can be used as the first selectde medicament in the third kind of analgesic.It is worth clinical adopting extensively.
出处
《实用癌症杂志》
1997年第1期48-49,共2页
The Practical Journal of Cancer
关键词
硫酸吗啡
控释片
镇痛剂
癌痛
Morphine sulphate Controlled release tablets Analgesics Cancer pain
