摘要
目的了解深圳学龄前儿童血脂的正常值、临界值、危险值及深圳学龄前儿童的血脂异常率。方法对深圳特区284名2～6岁学龄前儿童空腹12h以上抽静脉血检测三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白AI(ApoAI)、载脂蛋白B(ApoB)。结果2～6岁儿童TC、TG、HDL-C、LDL-C、ApoAI、ApoB的危险值分别为>5.83mmol/L,>1.29mmol/L,<1.44mmol/L,>3.28mmol/L,<1.38g/L,>1.14g/L。儿童血脂异常的总检出率为14.08%,以TC异常为主,不同年龄组儿童血脂异常率间差别无显著性意义(P>0.05);男童和女童的血脂异常率间差别无显著性意义(P>0.05)。结论血脂异常在2～6岁儿童中已存在一定比例,从儿童期开始高脂血症的预防对预防心血管病具有潜在效益。
Objective To explore the normal values, recommended borderline - up limit values, risk value of blood lipid and the prevalence of abnormal serum lipid in children aged 2 to 6 years old in Shenzhen. Methods After fasting for 12 hours in 284 children, their venous blood was drown, the serum levels of total cholesterol （TC） , triglyceride （ TG）, high - density lipoprotein cholesterol （HDL- C）, low h -density lipoprotein cholesterol （HDL -C）, apopliprotein AI （ApoAI）, apopliprotein B （ApoB） were assayed by using automatic biochemical instrument. Results For the lipid levels of 2 to 6 years, the risk values of TC, TG, LDL - C, ApoB were above 5. 83mmol/L, I. 29mmol/L, 3. 28mmol/L, 1.14g/L; and the risk value of HDL - C, ApoAI were below 1.44mmol/L, 1.38g/L, respectively. The prevalence of abnormal serum lipid was 14. 08%, especially in TC level, with no significant difference among different age groups of the child （ P 〉 0. 05 ）, and no significant difference between boys and girls （ P 〉 0. 05 ）, Conclusion There is a certain prevalence of abnormal blood lipid in children aged 2 to 6 years. Controlling abnormal blood lipid in children would be helpful to reduce risk factors resulting in cardiovascular disease.
出处
《中国全科医学》
CAS
CSCD
2007年第15期1245-1247,共3页
Chinese General Practice
基金
深圳市科技局立项课题(200603121)
关键词
学龄前儿童
血脂
脂蛋白
载脂蛋白
Preschool children
Serum - lipids
Lipoproteins
Apoliproteins
